Game List
Nintendo DS Lite
| Title | Developer(s) | Publisher(s) | First released |
|---|---|---|---|
| 007: Quantum of Solace | Vicarious Visions | Activision | October 31, 2008 (EU) |
| 1 vs. 100 | ECi | Destination Software | July 3, 2008 (NA) |
| 100 Classic Book Collection | Genius Sonority | Nintendo | December 26, 2008 (EU) |
| 101-in-1 Explosive Megamix | Nordcurrent | Atlus, Nordcurrent | November 28, 2008 (EU) |
| 2006 FIFA World Cup | Exient Entertainment | Electronic Arts | April 24, 2006 (NA) |
| 7 Wonders II | MumboJumbo | MumboJumbo | June 30, 2009 (NA) |
| 7 Wonders of the Ancient World | Hot Lava Games | MumboJumbo | September 17, 2007 (NA) |
| 7th Dragon | imageepoch | Sega | March 5, 2009 (JP) |
| 8Ball Allstars | Code Monkeys | Oxygen Games | August 7, 2009 (PAL) |
| A-Train DS | Artdink | Artdink | April 3, 2009 (JP) |
| Ace Attorney Investigations: Miles Edgeworth | Capcom | Capcom | May 28, 2009 (JP) |
| Ace Attorney Investigations 2 | Capcom | Capcom | February 3, 2011 (JP) |
| Actua Pool | Frontline Studios | Zoo Digital Publishing | January 1, 2007 (AU) |
| Advance Wars: Days of Ruin | Intelligent Systems | Nintendo | January 21, 2008 (PAL) |
| Advance Wars: Dual Strike | Intelligent Systems | Nintendo | August 22, 2005 (NA) |
| Adventure Time: Hey Ice King! Why'd You Steal Our Garbage?!! | WayForward Technologies | D3 Publisher | November 20, 2012 (NA) |
| AFL Mascot Manor | Wicked Witch Software | Tru Blu Games | July 2, 2009 (AUS) |
| Again | Cing | Tecmo | December 10, 2009 (JP) |
| Agatha Christie: The ABC Murders | DreamCatcher Games | DreamCatcher Games | November 12, 2009 (NA) |
| Age of Empires: Mythologies | Griptonite Games | THQ | November 24, 2008 (NA) |
| Age of Empires: The Age of Kings | Backbone Entertainment | Majesco Entertainment | February 14, 2006 (NA) |
| Air Traffic Chaos | Majesco Entertainment | Majesco Entertainment | July 30, 2008 (NA) |
| Alex Rider: Stormbreaker | Altron | THQ | July 7, 2006 (PAL) |
| Alice in Wonderland | Étranges Libellules | Disney Interactive Studios | March 2, 2010 (NA) |
| Aliens in the Attic | Engine Software | Playlogic | July 28, 2009 (NA) |
| Aliens Infestation | WayForward, Gearbox Software | Sega | September 29, 2011 (AUS) |
| All Kamen Rider: Rider Generation 2 | Bandai Namco Games | Bandai Namco Games | August 2, 2012 (JP) |
| All Star Cheer Squad | Gorilla Systems | THQ | November 11, 2008 (NA) |
| Allied Ace Pilots | Ghostlight | Ghostlight, Midas Interactive Entertainment | September 19, 2008 (PAL) |
| Alpha and Omega | Storm City Games | Lionsgate | September 14, 2010 (NA) |
| Alvin and the Chipmunks | Brash Entertainment | Brash Entertainment, Eidos Interactive | December 4, 2007 (NA) |
| Alvin and the Chipmunks: The Squeakquel | ImaginEngine | Majesco Entertainment | December 1, 2009 (NA) |
| The Aly & AJ Adventure | Frame Studios Interactive | Destination Software | October 15, 2007 (NA) |
| Amazing Adventures: The Forgotten Ruins | Black Lantern Studios | PopCap Games | November 11, 2008 (NA) |
| America's Next Top Model | Arts Software | Eidos Interactive | June 7, 2010 (NA) |
| America's Test Kitchen Let's Get Cooking | indieszero | Nintendo | March 28, 2010 (NA) |
| American Girl: Julie Finds a Way | THQ | THQ | December 3, 2007 (NA) |
| American Girl: Kit Mystery Challenge | THQ | THQ | June 23, 2008 (NA) |
| AMF Bowling Pinbusters! | 4J Studios | ZeniMax Media | July 7, 2008 (NA) |
| Angelique Duet | Koei | Koei | April 6, 2006 (JP) |
| Animal Boxing | Gammick Entertainment | Destineer, Gammick Entertainment | October 28, 2008 (NA) |
| Animal Crossing: Wild World | Nintendo | Nintendo | November 23, 2005 (JP) |
| Animal Genius | Big Blue Bubble | Scholastic, Ubisoft | September 25, 2007 (NA) |
| Animal Life: Africa | UIG Entertainment | UIG Entertainment | November 17, 2011 (PAL) |
| Animal Life: Australia | UIG Entertainment | UIG Entertainment | November 17, 2011 (PAL) |
| Animal Paradise | Agatsuma Entertainment | Empire Interactive | April 26, 2007 (JP) |
| Animal Paradise Wild | Empire Interactive | Zoo Games | October 6, 2009 (NA) |
| Animal Planet: Emergency Vets | Silverbirch Studios | Activision | March 13, 2009 (NA) |
| Animaniacs: Lights, Camera, Action | Ignition Entertainment | Warthog | August 4, 2005 (PAL) |
| AniMates | DK-Games | DreamCatcher Games, Lexicon Entertainment | July 14, 2007 (NA) |
| Ankh: Curse of the Scarab King | VIS Entertainment | Xider Games | September 17, 2008 (PAL) |
| Anno 1701: Dawn of Discovery | Keen Games | Disney Interactive Studios, Ubisoft | July 13, 2007 (PAL) |
| The Another World | Level-5, Studio Ghibli | Level-5 | December 9, 2010 (JP) |
| Ant Nation | Konami | Konami | July 14, 2009 (NA) |
| Apathy: Narugami Gakuen Toshi Densetsu Tantei Kyoku | Del | Arc System Works | October 25, 2007 (JP) |
| Apollo Justice: Ace Attorney | Capcom | Capcom | April 12, 2007 (JP) |
| Arctic Tale | Atomic Planet Entertainment | Destination Software, Zoo Digital Publishing | October 8, 2007 (NA) |
| Are You Smarter Than a 5th Grader: Make the Grade | THQ | THQ | October 20, 2008 (NA) |
| Arkanoid DS | Taito Corporation | Square Enix, Taito Corporation | December 6, 2007 (JP) |
| Army Men: Soldiers of Misfortune | Zoo Games | Zoo Games | October 10, 2008 (NA) |
| Art Academy | Headstrong Games | Nintendo | June 19, 2010 (JP) |
| Arthur and the Invisibles | Étranges Libellules, Neko Entertainment | Atari | January 9, 2007 (NA) |
| ASH: Archaic Sealed Heat | Mistwalker, Racjin | Nintendo | October 4, 2007 (JP) |
| Asoberu Eigo: Word Magic | Shingakusha | Shingakusha | December 25, 2008 (JP) |
| Asphalt Urban GT | Gameloft | Ubisoft | November 17, 2004 (NA) |
| Asphalt: Urban GT 2 | Game Source, Virtuous | Ubisoft | November 14, 2006 (NA) |
| Assassin's Creed: Altaïr's Chronicles | Gameloft | Ubisoft | February 5, 2008 (NA) |
| Assassin's Creed II: Discovery | Griptonite Games | Ubisoft | November 17, 2009 (NA) |
| Asterix & Obelix XXL 2 - Mission: Wifix | Mistic Software, Tate Interactive | Atari | November 1, 2006 (PAL) |
| Asterix at the Olympic Games | Étranges Libellules | Atari | February 29, 2008 (PAL) |
| Asterix Brain Trainer | Little Worlds Studio | Atari | June 27, 2008 (PAL) |
| Astro Boy: The Video Game | Art | D3 Publisher | October 20, 2009 (NA) |
| Astrology | Codemasters | Black Bean Games | July 3, 2009 (PAL) |
| Astrology DS | Sproing Media | Deep Silver | September 22, 2009 (NA) |
| Atari Greatest Hits Volume 1 | Atari | Code Mystics | November 2, 2010 (NA) |
| Atari Greatest Hits Volume 2 | Atari | Code Mystics | March 8, 2011 (NA) |
| Atelier Annie: Alchemists of Sera Island | Gust Corporation | Nippon Ichi Software | March 12, 2009 (NA) |
| Atsumare! Power Pro Kun no DS Koushien | Konami | Konami | August 3, 2006 (JP) |
| ATV: Quad Frenzy | Skyworks Technologies | Majesco Entertainment, THQ | November 14, 2005 (NA) |
| Avalon Code | Matrix Software | Marvelous Interactive, Rising Star Games, Xseed Games | November 1, 2008 (JP) |
| Avatar: The Last Airbender | THQ | THQ | October 10, 2006 (NA) |
| Avatar: The Last Airbender - Into the Inferno | THQ | THQ | October 17, 2008 (PAL) |
| Avatar: The Last Airbender - The Burning Earth | THQ | THQ | October 16, 2007 (NA) |
| Away Shuffle Dungeon | Artoon, Mistwalker | AQ Interactive, Majesco Entertainment, Virgin Play | October 16, 2008 (JP) |
| B Team: Metal Cartoon Squad | Most Wanted Entertainment | Virgin Play | February 20, 2009 (PAL) |
| B-17: Fortress in the Sky | Zoo Digital Publishing | Destination Software | June 19, 2007 (NA) |
| Baby Life | Deep Silver | Deep Silver | November 28, 2008 (NA) |
| Baby Pals | Crave Entertainment | Crave Entertainment, THQ | November 19, 2007 (NA) |
| Babysitting Mania | iWin | Majesco Entertainment | September 23, 2008 (NA) |
| Back at the Barnyard: Slop Bucket Games | THQ | THQ | October 20, 2008 (NA) |
| Backyard Baseball '09 | Humongous Entertainment | Atari | March 25, 2008 (NA) |
| Backyard Baseball '10 | Humongous Entertainment | Atari | March 26, 2009 (NA) |
| Backyard Basketball 2008 | Humongous Entertainment | Atari | September 25, 2007 (NA) |
| Backyard Football | Humongous Entertainment | Atari | October 23, 2007 (NA) |
| Backyard Football '09 | Humongous Entertainment | Atari | October 21, 2008 (NA) |
| Backyard Hockey | Mistic Software | Humongous Entertainment | October 2, 2007 (NA) |
| Bakugan Battle Brawlers | Now Production | Activision | October 20, 2009 (NA) |
| Bakugan Battle Brawlers: Battle Trainer | Now Production | Activision | March 23, 2010 (NA) |
| Bakugan: Defenders of the Core | Now Production | Activision, Sega | September 23, 2011 (EU) |
| Bakugan: Rise of the Resistance | Activision | Activision | September 23, 2011 (EU) |
| Bakuman: Mangaka e no Michi | Bandai Namco Games | Bandai Namco Games | December 15, 2011 (JP) |
| Bakumatsu Renka: Shinsengumi DS | D3 Publisher | D3 Publisher | November 27, 2008 (JP) |
| Balls of Fury | Black Lantern Studios | Destination Software, Zoo Digital Publishing | September 9, 2007 (NA) |
| Band Hero | Vicarious Visions | RedOctane | November 3, 2009 (NA) |
| Bangai-O Spirits | Treasure | D3 Publisher, Entertainment Software Publishing | March 19, 2008 (JP) |
| Barbie and the Three Musketeers | WayForward Technologies | Activision | November 3, 2009 (NA) |
| Barbie as the Island Princess | Human Soft | Activision | October 30, 2007 (NA) |
| Barbie: Dreamhouse Party | Torus Games | Little Orbit | November 12, 2013 (NA) |
| Barbie Fashion Show: An Eye for Style | Cyber Planet Interactive | Activision | September 23, 2008 (NA) |
| Barbie: Groom and Glam Pups | Game Machine Studios | THQ | November 16, 2010 (NA) |
| Barbie Horse Adventures: Riding Camp | Farmind, Pixel Tales | Activision | October 21, 2008 (NA) |
| Barbie in the 12 Dancing Princesses | WayForward Technologies | Activision | January 14, 2007 (NA) |
| Barbie: Jet, Set & Style! | THQ | THQ | September 20, 2011 (NA) |
| Barnyard Blast: Swine of the Night | Sanuk Games | Bigben Interactive, Destination Software, Neko Entertainment | February 15, 2008 (NA) |
| Bartender DS | Electronic Arts | Electronic Arts | September 27, 2007 (JP) |
| Batman: The Brave and the Bold - The Videogame | WayForward Technologies | Warner Bros. Interactive Entertainment | September 7, 2010 (NA) |
| Battle of Giants: Dinosaurs | Ubisoft Quebec | Ubisoft | October 14, 2008 (NA) |
| Battle of Giants: Dragons | Ubisoft Quebec | Ubisoft | September 29, 2009 (NA) |
| Battle of Giants: Mutant Insects | Ubisoft Quebec | Ubisoft | March 2, 2010 (NA) |
| Battles of Prince of Persia | Ubisoft Montreal | Ubisoft | December 6, 2005 (NA) |
| Battleship | Magic Pockets | Activision | April 20, 2012 (EU) |
| Battleship/Connect Four/Sorry!/Trouble | Gravity-I | Destination Software | August 17, 2006 (NA) |
| Beat City | Universomo | THQ | April 20, 2010 (NA) |
| The Bee Game | Midway Games | Midway Games | October 15, 2007 (NA) |
| Bee Movie Game | Vicarious Visions | Activision | November 16, 2007 (PAL) |
| Bejeweled Twist | PopCap | PopCap | January 18, 2010 (NA) |
| Bella Sara | Hidden City Games | Codemasters | September 26, 2008 (PAL) |
| Ben 10: Alien Force | 1st Playable Productions | D3 Publisher | October 28, 2008 (NA) |
| Ben 10 Alien Force: Vilgax Attacks | Papaya Studio | D3 Publisher | October 27, 2009 (NA) |
| Ben 10: Galactic Racing | Straight Right | D3 Publisher | October 18, 2011 (NA) |
| Ben 10: Omniverse | 1st Playable Productions | D3 Publisher | November 13, 2012 (NA) |
| Ben 10: Protector of Earth | 1st Playable Productions | D3 Publisher | October 30, 2007 (NA) |
| Ben 10 Ultimate Alien: Cosmic Destruction | Griptonite Games | D3 Publisher | October 5, 2010 (NA) |
| Berlitz English Dictionary | Koch Media | Koch Media | June 6, 2008 (PAL) |
| Best of Tests DS | Otaboo | Conspiracy Entertainment | March 4, 2008 (NA) |
| Betty Boop's Double Shift | Black Lantern Studios | Destination Software, Zoo Digital Publishing | October 19, 2007 (PAL) |
| Beyblade: Metal Fusion | Hudson Soft | Konami | December 3, 2009 (JP) |
| Beyblade: Metal Masters | Hudson Soft | Konami | July 15, 2010 (JP) |
| Big Bang Mini | Arkedo Studio | SouthPeak Games | January 1, 2009 (NA) |
| Big Brain Academy | Nintendo | Nintendo | June 30, 2005 (JP) |
| Big Hero 6 Battle in the Bay | 1st Playable Productions | GameMill Entertainment | October 28, 2014 (NA) |
| Big Mutha Truckers | Raylight Studios | Destination Software, Zoo Digital Publishing | October 19, 2005 (NA) |
| Bigfoot: Collision Course | Destination Software | Zoo Games | December 2, 2008 (PAL,NA) |
| The Bigs 2 | Blue Castle Games | 2K Sports | July 7, 2009 (NA) |
| Biker Mice from Mars | Full Fat | The Game Factory | February 9, 2007 (PAL) |
| The Billiards | Agenda | 505 Games, D3 Publisher | June 30, 2005 (JP) |
| Bionicle Heroes | Amaze Entertainment | Eidos Interactive, Electronic Arts | November 14, 2006 (NA) |
| Black Butler: Phantom & Ghost | Square Enix | Square Enix | March 19, 2009 (JP) |
| Black Sigil: Blade of the Exiled | Studio Archcraft | Graffiti Entertainment | June 9, 2009 (NA) |
| Blades of Thunder II | CokeM Interactive | Summitsoft Entertainment | April 18, 2006 (NA) |
| Blazer Drive | Sega | Sega | December 4, 2008 (JP) |
| Bleach: Dark Souls | Treasure | Sega | February 15, 2007 (JP) |
| Bleach DS 4th: Flame Bringer | Sega | Sega | August 6, 2009 (JP) |
| Bleach: The 3rd Phantom | Sega | Sega | June 26, 2008 (JP) |
| Bleach: The Blade of Fate | Treasure | Sega | January 26, 2006 (JP) |
| Blood Bowl | Cyanide | Focus Home Interactive | September 18, 2009 (EU) |
| Blood of Bahamut | Think & Feel | Square Enix | August 6, 2009 (JP) |
| Blue Dragon Plus | Brownie Brown, feelplus, Mistwalker | AQ Interactive, Ignition Entertainment | September 4, 2008 (JP) |
| Blue Dragon: Awakened Shadow | Mistwalker, tri-Crescendo | Namco Bandai Games, D3 Publisher | October 8, 2009 (JP) |
| Bob the Builder: Festival of Fun | Blast! Entertainment | Blast! Entertainment | September 26, 2008 (PAL) |
| Boing! Docomodake DS | AQ Interactive, Suzak Inc. | AQ Interactive, Ignition Entertainment | December 6, 2007 (JP) |
| Bokujō Monogatari: Yōkoso! Kaze no Bazaar e | Marvelous Interactive | Marvelous Interactive | December 18, 2008 (JP) |
| Bolt | Avalanche Software | Disney Interactive Studios | November 18, 2008 (NA) |
| Bomberman | Hudson Soft | Hudson Soft, Ubisoft | May 19, 2005 (JP) |
| Bomberman 2 | Hudson Soft | Hudson Soft | December 4, 2008 (JP) |
| Bomberman Land Touch! | Hudson Soft | Atlus, Hudson Soft, Nintendo, Red Ant Enterprises, Rising Star Games | July 20, 2006 (JP) |
| Bomberman Land Touch! 2 | Hudson Soft | Hudson Soft, Rising Star Games | July 19, 2007 (JP) |
| Bomberman Story DS | Hudson Soft | Hudson Soft, Rising Star Games | March 21, 2007 (JP) |
| Boogie | EA Montreal | Electronic Arts | November 27, 2007 (NA) |
| Boulder Dash: Rocks! | 10tacle Studios | 10tacle Studios, QV Software | November 23, 2007 (PAL) |
| Brain Age: Train Your Brain in Minutes a Day! | Nintendo | Nintendo | May 19, 2005 (JP) |
| Brain Age 2: More Training in Minutes a Day! | Nintendo | Nintendo | December 29, 2005 (JP) |
| Brain Assist | Sega | Sega | June 21, 2007 (JP) |
| Brain Boost: Beta Wave | Interchannel | 505 Games, Interchannel, Majesco Entertainment | November 23, 2005 (JP) |
| Brain Boost: Gamma Wave | Interchannel | Interchannel, Majesco Entertainment | November 23, 2005 (JP) |
| Brain Buster Puzzle Pak | Agetec, Nikoli | 505 Games, Agetec, Jaleco Entertainment | September 28, 2006 (JP) |
| Brain Challenge | Gameloft | Gameloft, Ubisoft | January 8, 2008 (NA) |
| Brain Quest Grades 3 & 4 | Electronic Arts | Electronic Arts | September 22, 2008 (NA) |
| Brain Quest Grades 5 & 6 | Electronic Arts | Electronic Arts | September 22, 2008 (NA) |
| Brain Voyage | Razorback Developments | Eidos Interactive | April 11, 2008 (PAL) |
| Bratz 4 Real | THQ | THQ | November 5, 2007 (NA) |
| Bratz: Girlz Really Rock | Barking Lizards Technologies | THQ | October 9, 2008 (NA) |
| Bratz Kidz | Neko Entertainment | The Game Factory | October 30, 2008 (AU) |
| Bratz Ponyz | The Game Factory | The Game Factory | July 30, 2007 (NA) |
| Bratz Ponyz 2 | Neko Entertainment | The Game Factory | September 9, 2008 (NA) |
| Bratz: Forever Diamondz | Barking Lizards Technologies | THQ | September 18, 2006 (NA) |
| Bratz: Super Babyz | Creat Studios | THQ | February 15, 2008 (EU) |
| Brave Story: My Dreams and Wishes | Namco Bandai Games | Bandai | July 6, 2006 (JP) |
| Brave: Shaman's Challenge | Collision Studios | Evolved Games, SouthPeak Games | August 28, 2009 (EU) |
| Break 'Em All | Warashi | 505 Games, D3 Publisher | October 27, 2005 (JP) |
| Broken Sword: The Shadow of the Templars | Revolution Software | Ubisoft | March 1, 2009 (PAL) |
| Brothers in Arms DS | Gameloft | Ubisoft | June 8, 2007 (NA) |
| Bubble Bobble Double Shot | Dreams | Ignition Entertainment, Rising Star Games | March 23, 2007 (PAL) |
| Bubble Bobble Revolution | Dreams | Codemasters, Rising Star Games, Taito Corporation | November 24, 2005 (JP) |
| Bubble Guppies | Black Lantern Studios | 2K Play | November 6, 2012 (NA) |
| Buffy the Vampire Slayer: Sacrifice | Beast | 505 Games | November 1, 2008 (PAL) |
| Build-a-lot | HipSoft | MumboJumbo | December 9, 2008 (NA) |
| Build-A-Bear Workshop | Neko Entertainment | The Game Factory | November 5, 2007 (NA) |
| Burnout Legends | Visual Impact | Electronic Arts | December 9, 2005 (NA) |
| Bust-a-Move DS | Happy Happening | 505 Games, Majesco Entertainment, Taito Corporation | December 6, 2005 (NA) |
| C.O.P. The Recruit | VD-Dev | Ubisoft | March 25, 2009 (NA) |
| C.O.R.E. | NoWay Studio | Graffiti Entertainment | July 7, 2009 (NA) |
| Cake Mania | Digital Embryo | Majesco Entertainment | April 9, 2007 (NA) |
| Cake Mania: Main Street | Digital Embryo | Majesco Entertainment | May 24, 2011 (NA) |
| Cake Mania 2 | Digital Embryo | Majesco Entertainment | June 24, 2008 (NA) |
| Cake Mania 3 | Digital Embryo | Majesco Entertainment | October 9, 2010 (NA) |
| Call of Duty 4: Modern Warfare | n-Space | Activision | October 13, 2009 (NA) |
| Call of Duty: Black Ops | n-Space | Activision | November 9, 2010 (NA) |
| Call of Duty: Modern Warfare: Mobilized | n-Space | Activision | November 10, 2009 (NA) |
| Call of Duty: Modern Warfare 3 - Defiance | n-Space | Activision | November 8, 2011 (NA,PAL) |
| Call of Duty: World at War | n-Space | Activision, Activision Blizzard | November 11, 2008 (NA) |
| Camping Mama: Outdoor Adventures | Cooking Mama Limited | Majesco Entertainment | July 14, 2011 (JP) |
| Candy Factory | Destineer | Destineer | October 21, 2008 (NA) |
| Captain America: Super Soldier | Griptonite Games | Sega | July 14, 2011 (AU) |
| Captain Morgane and the Golden Turtle | Wizarbox | Reef Entertainment | November 11, 2012 (PAL) |
| Captain Tsubasa: Gekito no Kiseki | Konami | Konami | March 16, 2010 (JP) |
| Card Game 9 | Taito Corporation | Taito Corporation | August 31, 2006 (JP) |
| Carnival Games | Cat Daddy Games | 2K Games, Global Star Software | July 8, 2008 (NA) |
| Cartoon Network Racing | Firebrand Games | The Game Factory | December 4, 2006 (NA) |
| Casper's Scare School | Blast! Entertainment | Blast! Entertainment | September 26, 2008 (PAL) |
| Castlevania: Dawn of Sorrow | Konami | Konami | August 25, 2005 (JP) |
| Castlevania: Order of Ecclesia | Konami | Konami | October 21, 2008 (NA) |
| Castlevania: Portrait of Ruin | Konami | Konami | November 16, 2006 (JP) |
| Catz | Powerhead | Ubisoft | November 30, 2006 (NA) |
| Chainz Galaxy | MumboJumbo | Global Software Publishing | November 18, 2011 (PAL) |
| Chameleon: To Dye For! | Starfish SD | 505 Games, Starfish SD, Tommo, UFO Interactive Games | October 12, 2006 (JP) |
| Championship Pony | Coyote Console | Destination Software | March 20, 2008 (NA) |
| Chao Dream Touch! Happy Anniversary | Marvelous Interactive | Marvelous Interactive | December 7, 2006 (JP) |
| Chaotic: Shadow Warriors | Fun Labs | Activision | November 10, 2009 (NA) |
| Charlotte's Web | Backbone Entertainment | Sega | November 14, 2006 (NA) |
| The Cheetah Girls: Passport to Stardom | Handheld Games | Disney Interactive Studios | August 13, 2008 (NA) |
| The Cheetah Girls: Pop Star Sensations | Disney Interactive Studios | Buena Vista Games | October 9, 2007 (NA) |
| Chessmaster: The Art of Learning | Ubisoft | Ubisoft | October 23, 2007 (NA) |
| Chibi Maruko-chan DS Maru-chan no Machi | Banpresto | Namco Bandai Games | February 5, 2009 (JP) |
| Chibi-Robo!: Park Patrol | Skip Ltd. | Nintendo | July 5, 2007 (JP) |
| Chicken Hunter | Phenomedia | MumboJumbo | March 4, 2008 (NA) |
| Chicken Shoot | Frontline Studios | Destination Software, Zoo Digital Publishing | July 10, 2007 (NA) |
| Children of Mana | Next Entertainment | Nintendo, Square Enix | March 2, 2006 (JP) |
| Chōsōjū Mecha MG | Sandlot | Nintendo | September 2, 2006 (JP) |
| Chou!! Nep League DS | Jaleco Entertainment | Jaleco Entertainment | March 16, 2006 (JP) |
| The Chronicles of Narnia: Prince Caspian | Traveller's Tales | Disney Interactive Studios | May 15, 2008 (NA) |
| The Chronicles of Narnia: The Lion, the Witch and the Wardrobe | Traveller's Tales | Buena Vista Games, D3 Publisher, Disney Interactive Studios | November 14, 2005 (PAL) |
| Chrono Trigger | TOSE | Square Enix | November 20, 2008 (JP) |
| Chronos Twin | EnjoyUp | Oxygen Games | October 2, 2007 (PAL) |
| Chrysler Classic Racing | EM Studios | Zoo Games | November 25, 2008 (NA) |
| Cid to Chocobo no Fushigina Dungeon Toki Wasure no Meikyū DS+ | Square Enix | Square Enix | October 30, 2008 (JP) |
| City Life | Ubisoft | Ubisoft | August 7, 2009 (EU) |
| Cinnamon Ball DS | Rocket Company | Rocket Company | July 12, 2007 (JP) |
| Claymore: Gigan no Majo | Digital Works Entertainment | Digital Works Entertainment | May 28, 2009 (JP) |
| Clever Kids: Dino Land | Gamerholix | Midas Interactive Entertainment | November 2, 2007 (PAL) |
| Clever Kids: Farmyard Fun | Gamerholix | Midas Interactive Entertainment | October 17, 2008 (PAL) |
| Clever Kids: Pirates | Gamerholix | Midas Interactive Entertainment | October 17, 2008 (PAL) |
| Clever Kids: Pony World | Gamerholix | Midas Interactive Entertainment | November 2, 2007 (PAL) |
| The Clique: Diss and Make-Up | Gorilla Systems Corp. | Warner Bros. Interactive Entertainment | August 25, 2009 (NA) |
| Cloudy with a Chance of Meatballs | Ubisoft | Ubisoft | September 11, 2009 (EU) |
| Club Penguin: Elite Penguin Force | 1st Playable Productions | Disney Interactive Studios | November 11, 2008 (NA) |
| Clubhouse Games | Agenda | Nintendo | September 29, 2006 (PAL) |
| Clue / Mouse Trap / Perfection / Aggravation | Gravity-i | Destination Software | November 20, 2007 (NA) |
| Cocoto Kart Racer | Neko Entertainment | Bigben Interactive, Conspiracy Entertainment, Kemco, Midway Games | January 1, 2005 (PAL) |
| Code Geass: Lelouch of the Rebellion | Crafts & Meister | Bandai Namco Games | March 27, 2008 (JP) |
| Code Lyoko | DC Studios | The Game Factory | May 15, 2007 (NA) |
| Code Lyoko: Fall of X.A.N.A. | Neko Entertainment | The Game Factory | June 6, 2008 (PAL) |
| Cokoro no Cokoron | h.a.n.d. | Bandai Namco Games | July 14, 2011 (JP) |
| Colin McRae: Dirt 2 | Codemasters | Codemasters | September 8, 2009 (NA) |
| Colour Cross | Rising Star Games | Zoo Games | November 28, 2008 (PAL) |
| Command and Destroy | Cypron Studios | Destination Software, Zoo Digital Publishing | February 15, 2008 (NA) |
| Commando: Steel Disaster | Mana Computer Software | Lexicon Entertainment, XS Games | May 30, 2008 (PAL) |
| Contact | Grasshopper Manufacture | Atlus, Marvelous Interactive, Rising Star Games | March 30, 2006 (JP) |
| Contra 4 | WayForward Technologies | Konami | November 13, 2007 (NA) |
| Cookie & Cream | From Software | 505 Games, Agetec, From Software | June 28, 2007 (JP) |
| Cooking Mama | Cooking Mama Limited | 505 Games, Majesco Entertainment, Taito Corporation | March 23, 2006 (JP) |
| Cooking Mama 2: Dinner with Friends | Cooking Mama Limited | 505 Games, Majesco Entertainment, Taito Corporation | November 13, 2007 (NA) |
| Cooking Mama 3: Shop & Chop | Taito Corporation | 505 Games, Taito Corporation | October 20, 2009 (NA) |
| Coraline | Art | D3 Publisher | January 27, 2009 (NA) |
| Corvette Evolution GT | Milestone | Black Bean Games | January 15, 2008 (NA) |
| Countdown: The Game | Mindscape | Mindscape | November 6, 2009 (EU) |
| Cradle of Rome | Cerasus Media | D3 Publisher, Rising Star Games | November 18, 2008 (NA) |
| Crash Boom Bang! | Dimps Corporation | Sierra Entertainment, VU Games | July 27, 2006 (JP) |
| Crash of the Titans | Amaze Entertainment | Sierra Entertainment | October 19, 2007 (PAL) |
| Crash: Mind Over Mutant | Radical Entertainment | Sierra Entertainment, Activision Blizzard | October 29, 2008 (NA) |
| Crayola Treasure Adventures | Crave Entertainment | Crave Entertainment, Ignition Entertainment | October 1, 2007 (NA) |
| Crazy Frog Racer | Digital Jesters | Atari, Mercury Games | November 3, 2006 (PAL) |
| Crazy Machines | DTP Entertainment | DTP Entertainment | October 10, 2008 (EU) |
| Crazy Pig | Mindscape | Mindscape | November 30, 2007 (PAL) |
| Crimson Room | Takagism | Success | December 20, 2007 (JP) |
| The Croods: Prehistoric Party! | Torus Games | D3 Publisher | March 19, 2013 (NA) |
| Crosswords DS | Nuevo Retro Games | Deep Silver, Nintendo | May 5, 2008 (NA) |
| CSI: Dark Motives | Powerhead Games | Ubisoft | November 2, 2007 (PAL) |
| CSI: Deadly Intent | Telltale Games | Ubisoft | October 27, 2009 (NA) |
| CSI: Unsolved | Other Ocean | Ubisoft | November 23, 2010 (NA) |
| Culdcept DS | Sega | Sega | October 16, 2008 (JP) |
| Custom Battler Bomberman | December 4, 2008 (JP) | ||
| Custom Beat Battle: Draglade 2 | July 10, 2008 (JP) | ||
| Curling DS | Rocket Company | Rocket Company, Ubisoft | November 22, 2006 (JP) |
| Custom Mahjong | Success | Success | December 20, 2007 (JP) |
| Custom Robo Arena | Noise | Nintendo | October 19, 2006 (JP) |
| D.Gray-man: Kami no Shitotachi | Konami | Konami | March 29, 2007 (JP) |
| Daigasso! Band-Brothers | Nintendo | Nintendo | December 2, 2004 (JP) |
| Daigasso! Band Brothers DX | June 26, 2008 (JP) | ||
| Daikoukai Jidai IV: Rota Nova | Koei | Koei | March 2, 2006 (JP) |
| Daisenryaku DS | Genki | Genki | May 25, 2006 (JP) |
| Dalmatians 4 | Phoenix Software | Phoenix Software | October 24, 2008 (EU) |
| Dancing with the Stars: We Dance! | Jet Black Games | Activision | October 21, 2008 (NA) |
| Danny Phantom: Urban Jungle | THQ | THQ | September 19, 2006 (NA) |
| The Dark Spire | Success | Atlus, Success | May 22, 2008 (JP) |
| Datenshi no Amai Yuuwaku x Kaikan Phase | FuRyu | FuRyu | February 18, 2010 (JP) |
| Dawn of Heroes | Wicked Studios | Majesco Entertainment | September 13, 2010 (NA) |
| Days of Memories | SNK Playmore | SNK Playmore | June 14, 2007 (JP) |
| Days of Memories 2 | SNK Playmore | SNK Playmore | April 24, 2008 (JP) |
| Days of Memories 3 | SNK Playmore | SNK Playmore | May 28, 2009 (JP) |
| De Blob 2 | Halfbrick | THQ | February 22, 2011 (NA) |
| Deal or No Deal | Gravity-i | Destination Software, Mindscape | July 23, 2007 (NA) |
| Deal or No Deal: Special Edition | Gravity-i | Destination Software | September 13, 2010 (NA) |
| Deal or No Deal: The Banker is Back! | Gravity-i | Mindscape | November 14, 2008 (EU) |
| Death Note Kira's Game | Konami | Konami | February 15, 2007 (JP) |
| Death, Jr. and the Science Fair of Doom | Backbone Entertainment | Konami | May 22, 2007 (NA) |
| Deca Sports DS | Hudson Soft | Hudson Soft | October 17, 2008 (PAL) |
| Deep Aquarium | Ertain | Ertain | March 28, 2008 (NA) |
| Deep Labyrinth | Interactive Brains | 505 Games, Atlus, Interactive Brains | March 23, 2006 (JP) |
| Defendin' DePenguin | Crave Entertainment | Crave Entertainment | September 2, 2008 (NA) |
| Dekitayo Mama! Mitsugo no Kuma-San - Onna no Ko | Starfish SD | Starfish SD | April 15, 2010 (JP) |
| Deltora Quest | Namco Bandai Games | Namco Bandai Games | September 20, 2007 (JP) |
| Demashita! Powerpuff Girls Z: The Game | Namco Bandai Games | Namco Bandai Games | June 14, 2007 (JP) |
| Dementium II | Renegade Kid | SouthPeak Games, Intergrow | May 4, 2010 (NA) |
| Dementium: The Ward | Renegade Kid | Gamecock Media Group, Interchannel | June 26, 2008 (JP) |
| Dengeki Gakuen RPG: Cross of Venus | Pegasus Japan | ASCII Media Works | March 19, 2009 (JP) |
| Dengeki Gakuen RPG: Cross of Venus Special | Pegasus Japan | ASCII Media Works | February 10, 2011 (JP) |
| Densetsu no Stafy 4 | TOSE | Nintendo | April 13, 2006 (JP) |
| Densha de Go! Tokubetsu-hen: Fukkatsu! Shouwa no Yamanotesen | Square Enix, Taito | Square Enix | July 22, 2010 (JP) |
| Derby Stallion DS | Enterbrain | Enterbrain | June 26, 2008 (JP) |
| Desktop Tower Defense | THQ | THQ | May 11, 2009 (NA) |
| Devilish: Ball Bounder | Starfish SD | 505 Games, Starfish SD, UFO Interactive Games | April 28, 2005 (JP) |
| Di-Gata Defenders | The Game Factory | The Game Factory | May 13, 2008 (NA) |
| Diabolik: The Original Sin | Artematica | Black Bean Games | June 26, 2009 (EU) |
| Diamond Trust of London | Jason Rohrer | indiePub | August 7, 2012 (NA) |
| Diary Girl | Konami | Konami | March 18, 2008 (NA) |
| Diddy Kong Racing DS | Rare | Nintendo | February 5, 2007 (NA) |
| Dig Dug: Digging Strike | Namco | Atari, Namco | September 8, 2005 (JP) |
| Digimon World Championship | Namco Bandai Games | Namco Bandai Games | February 14, 2008 (JP) |
| Digimon World DS | Namco Bandai Games | Namco Bandai Games | June 15, 2006 (JP) |
| Digimon World: Dawn | Namco Bandai Games | Namco Bandai Games | March 29, 2007 (JP) |
| Digimon World: Dusk | Namco Bandai Games | Namco Bandai Games | March 29, 2007 (JP) |
| Diner Dash: Flo on the Go | PlayFirst | PlayFirst | September 18, 2009 (EU) |
| Diner Dash: Sizzle & Serve | GameLab, PlayFirst | Eidos Interactive | May 4, 2007 (PAL) |
| Dino Master | Creative Office | Eidos Interactive, Majesco Entertainment, Taito Corporation | September 22, 2005 (JP) |
| Dinosaur King | Sega | Sega | November 11, 2007 (JP) |
| Disgaea DS | Nippon Ichi Software | Nippon Ichi Software, NIS America, Square Enix | June 26, 2008 (JP) |
| Disney Camp Rock: The Final Jam | Disney Interactive Studios | Disney Interactive Studios | August 31, 2010 (NA) |
| Disney Friends | Amaze Entertainment, Walt Disney Interactive | Disney Interactive Studios, Walt Disney Interactive | October 19, 2007 (PAL) |
| Disney Frozen: Olaf's Quest | 1st Playable Productions | GameMill Entertainment | November 19, 2013 (NA) |
| Disney/Pixar's Cars | Helixe | THQ | June 6, 2006 (NA) |
| Disney/Pixar's Cars Mater-National Championship | Tantalus Interactive | THQ | October 29, 2007 (NA) |
| Disney/Pixar's Cars Race-O-Rama | Rainbow Studios | THQ | October 12, 2009 (NA) |
| Disney/Pixar's Finding Nemo: Escape to the Big Blue | Altron | Sega, THQ | February 9, 2006 (NA) |
| Disney Planes | Tose | Disney Interactive Studios | August 6, 2013 (NA) |
| Disney Princess: Magical Jewels | 1st Playable Productions | Disney Interactive Studios | October 16, 2007 (NA) |
| Disney's American Dragon: Jake Long, Attack of the Dark Dragon | WayForward Technologies | Buena Vista Games | October 12, 2006 (NA) |
| Disney's Chicken Little: Ace in Action | Disney Interactive Studios | Buena Vista Games, Disney Interactive Studios | November 9, 2006 (NA) |
| Disney's A Christmas Carol | Sumo Digital | Disney Interactive Studios | November 3, 2009 (NA) |
| Disney's Cory in the House | Handheld Games | Disney Interactive Studios | April 15, 2008 (NA) |
| Disney's Herbie Rescue Rally | Buena Vista Games | Disney Interactive Studios | March 15, 2007 (NA) |
| Disney's Kim Possible: Global Gemini | Artificial Mind and Movement | Buena Vista Games, Disney Interactive Studios | February 9, 2007 (EU) |
| Disney's Kim Possible: Kimmunicator | Artificial Mind and Movement | Buena Vista Games, Disney Interactive Studios | November 9, 2005 (NA) |
| Disney's The Little Mermaid: Ariel's Undersea Adventure | Gorilla Systems | Buena Vista Games, Disney Interactive Studios | October 2, 2006 (NA) |
| Disney's Meet the Robinsons | Buena Vista Games | Disney Interactive Studios | March 27, 2007 (NA) |
| Disney's That's So Raven: Psychic on the Scene | Handheld Games | Buena Vista Games | November 2, 2006 (NA) |
| DK Jungle Climber | Paon | Nintendo | August 9, 2007 (JP) |
| Doctor Who: Evacuation Earth | Asylum Entertainment | Asylum Entertainment | November 12, 2010 (EU) |
| Dogz | MTO | Ubisoft | November 22, 2006 (NA) |
| Dogz: Happy House | MTO | MTO | April 27, 2006 (JP) |
| Dokapon Journey | Sting Entertainment | Atlus, Sting Entertainment | July 29, 2008 (JP) |
| Doki Doki Majo Shinpan! | SNK Playmore | SNK Playmore | July 5, 2007 (JP) |
| Doki Doki Majo Shinpan 2 Duo | SNK Playmore | SNK Playmore | July 31, 2008 (JP) |
| Doki Majo Plus | SNK Playmore | SNK Playmore | July 30, 2009 (JP) |
| Dolphin Island: Underwater Adventures | Magic Pockets | Ubisoft | October 30, 2009 (EU) |
| Don King Boxing | Venom Games | 2K Games, 2K Sports | March 27, 2009 (EU) |
| Doodle Hex | Tragnarion Studios | Disney Interactive Studios, Tragnarion Studios, Pinnacle | July 11, 2008 (EU) |
| Doodle Jump Journey | CokeM Interactive | GameMill Entertainment | October 29, 2013 (NA) |
| Dora the Explorer: Dora Saves the Mermaids | Black Lantern Studios | 2K Play | November 5, 2007 (NA) |
| Dora the Explorer: Dora Saves the Snow Princess | Black Lantern Studios | 2K Play, Take-Two Interactive | October 3, 2008 (PAL) |
| Dorabase: Dramatic Stadium | Namco Bandai Games | Namco Bandai Games | December 20, 2007 (JP) |
| Double Sequence: The Q-Virus Invasion | Next Wave Team | Destination Software, Zoo Digital Publishing | April 1, 2008 (NA) |
| Dr. Seuss: How The Grinch Stole Christmas! | CokeM Interactive | Delphine Software International, Zoo Digital Publishing | November 8, 2007 (NA) |
| Dr. Slump: Arale-Chan | Namco Bandai Games | Namco Bandai Games | October 30, 2008 (JP) |
| Draglade | Dimps Corporation | 505 Games, Atlus, Banpresto | May 17, 2007 (JP) |
| Draglade 2 | Dimps Corporation | Namco Bandai Games | July 10, 2008 (NA) |
| Dragon Ball Z: Attack of the Saiyans | Monolith Soft | Atari, Namco Bandai Games | April 29, 2009 (JP) |
| Dragon Ball Z: Harukanaru Densetsu | Namco Bandai Games | Atari, Namco Bandai Games | March 21, 2007 (JP) |
| Dragon Ball Z: Supersonic Warriors 2 | Cavia | Atari, Bandai | November 20, 2005 (NA) |
| Dragon Ball: Origins | Game Republic | Atari, Namco Bandai Games | September 18, 2008 (JP) |
| Dragon Booster | Konami | Konami | December 28, 2005 (NA) |
| Dragon Hunters | Engine Software | Playlogic | April 11, 2008 (PAL) |
| Dragon Quest IV: Chapters of the Chosen | ArtePiazza | Square Enix | November 22, 2007 (JP) |
| Dragon Quest V: Hand of the Heavenly Bride | ArtePiazza | Square Enix | July 17, 2008 (JP) |
| Dragon Quest VI: Realms of Revelation | ArtePiazza | Square Enix | January 28, 2010 (JP) |
| Dragon Quest IX: Sentinels of the Starry Skies | Level-5 | Square Enix | July 11, 2009 (JP) |
| Dragon Quest Heroes: Rocket Slime | Square Enix, TOSE | Square Enix | December 1, 2005 (JP) |
| Dragon Quest Monsters: Joker | TOSE | Square Enix | December 28, 2006 (JP) |
| Dragon Quest Monsters: Joker 2 | TOSE | Square Enix | April 28, 2010 (JP) |
| Dragon Quest Monsters: Joker 2 Professional | TOSE | Square Enix | March 31, 2011 (JP) |
| Dragon Tamer Sound Spirit | Namco Bandai Games | Namco Bandai Games | November 1, 2007 (JP) |
| Dragon Zakura DS | EA Japan | Electronic Arts | March 8, 2007 (JP) |
| Dragon's Lair | United Coders, Wizardly Engineering | Conspiracy Entertainment | November 21, 2009 (NA) |
| Dragon's Lair II: Time Warp | United Coders | Conspiracy Entertainment | December 20, 2010 (NA) |
| Dragonology | Codemasters | Codemasters | November 6, 2009 (EU) |
| Drake & Josh: Talent Showdown | THQ | THQ | July 30, 2007 (NA) |
| Drawn to Life | 5TH Cell | Agatsuma Entertainment, THQ | September 10, 2007 (NA) |
| Drawn to Life: SpongeBob SquarePants Edition | Altron | THQ | September 15, 2008 (NA) |
| Drawn to Life: The Next Chapter | 5TH Cell | THQ | October 8, 2009 (AU) |
| Dream Pinball 3D | TopWare Interactive | SouthPeak Games | April 24, 2008 (NA) |
| Drivers' Ed Portable | TBA | DreamCatcher Interactive | October 17, 2008 (PAL) |
| Driving Theory Training | Anuman Interactive | Atari | August 29, 2008 (PAL) |
| Drone Tactics | Success | Atlus, Success | August 2, 2007 (JP) |
| DropCast | Mikoishi | THQ | September 22, 2008 (NA) |
| DS Rakubiki Jiten | Nintendo | Nintendo | June 16, 2005 (JP) |
| Ducati Moto | 4J Studios | Vir2L Studios | July 1, 2008 (NA) |
| Duel Love: Koisuru Otome wa Shōri no Megami | Namco Bandai Games | Namco Bandai Games | March 13, 2008 (JP) |
| Duke Nukem: Critical Mass | Apogee Software | Deep Silver | April 8, 2011 (EU) |
| Dungeon Explorer: Warriors of Ancient Arts | Hudson Soft | Hudson Soft, Rising Star Games | November 15, 2007 (JP) |
| Dungeon of Windaria | Compile Heart | Compile Heart | May 15, 2008 (JP) |
| Dynasty Warriors DS: Fighter's Battle | Koei | Koei | April 5, 2007 (JP) |
| EA Playground | EA Canada | Electronic Arts | October 23, 2007 (NA) |
| Eco Creatures: Save the Forest | Bergsala Lightweight | Interchannel, Majesco Entertainment, Rising Star Games | August 23, 2007 (JP) |
| Ed, Edd n Eddy: Scam of the Century | Art | D3 Publisher | October 23, 2007 (NA) |
| Edo Bunka Rekishi Kentei | Marvelous Entertainment | Marvelous Entertainment | March 13, 2008 (JP) |
| Egg Monster Hero | Square Enix | Square Enix | March 24, 2005 (JP) |
| Elebits: The Adventures of Kai and Zero | Konami | Konami | December 11, 2008 (JP) |
| Electroplankton | Indies Zero | Nintendo | April 7, 2005 (JP) |
| Elemental Monster | Hudson Soft | Hudson Soft | September 20, 2007 (JP) |
| Elements of Destruction | Black Lantern Studios | THQ | December 17, 2007 (NA) |
| Elf Bowling 1 & 2 | Ignition Entertainment | Ignition Entertainment | December 1, 2005 (NA) |
| Elite Beat Agents | iNiS | Nintendo | November 6, 2006 (NA) |
| Elite Forces: Unit 77 | Gammick Entertainment | Deep Silver | February 27, 2009 (NA) |
| Elminage DS Remix: Yami no Miko to Kamigami no Yubiwa | Opera House | Starfish SD | November 13, 2008 (JP) |
| Emblem of Gundam | Namco Bandai Games | Namco Bandai Games | May 1, 2008 (JP) |
| Emma at the Farm | Nobilis | Aspyr Media | November 11, 2008 (PAL) |
| Emma in the Mountains | Nobilis | Aspyr Media | November 11, 2008 (NA) |
| Enchanted | Altron | Disney Interactive Studios | November 13, 2007 (NA) |
| Ener-G Dance Squad | Lexis Numerique | Ubisoft | October 21, 2008 (NA) |
| Ener-G Gym Rockets | 1st Playable Productions | Ubisoft | October 21, 2008 (NA) |
| Ener-G Horse Riders | Lexis Numerique | Ubisoft | October 21, 2008 (NA) |
| English Training: Have Fun Improving Your Skills! | PLATO | Nintendo | January 26, 2006 (JP) |
| Equestrian Training | Atari | Atari | November 11, 2008 (PAL) |
| Eragon | Amaze Entertainment | Vivendi Games | November 14, 2006 (NA) |
| Essential Sudoku DS | Essential Games | D3 Publisher | October 27, 2006 (NA) |
| Etrian Odyssey | Atlus, Lancarse | Atlus, Nintendo | January 18, 2007 (JP) |
| Etrian Odyssey II: Heroes of Lagaard | Atlus, Lancarse | Atlus | February 21, 2008 (JP) |
| Etrian Odyssey III: The Drowned City | Atlus | Atlus | April 1, 2010 (JP) |
| Exit | Taito Corporation | Square Enix, Taito Corporation, Ubisoft | January 24, 2008 (JP) |
| Eyeshield 21: MAX Devil Power | Nintendo | Nintendo | February 2, 2006 (JP) |
| F24: Stealth Fighter | Majesco Entertainment | Eidos Interactive, Majesco Entertainment | February 20, 2007 (NA) |
| Fab 5 Soccer | Destineer | Destineer | April 11, 2008 (NA) |
| Face Training | Intelligent Systems | Nintendo | August 2, 2007 (JP) |
| Family Feud | Ubisoft | Ubisoft | September 29, 2009 (NA) |
| Family Game Night | Electronic Arts | Electronic Arts | October 26, 2009 (NA) |
| Family Park Tycoon | Visual Imagination Software | Astragon | November 17, 2008 (PAL) |
| Fantastic Four: Rise of the Silver Surfer | 7 Studios | 2K Games, Take-Two Interactive | June 15, 2007 (NA,PAL) |
| Fantasy Aquarium | Destineer | Mercury Games, Destineer | December 11, 2007 (PAL) |
| Fashion Designer: Style Icon | Creative Pattern | 505 Games | November 9, 2007 (PAL) |
| Feel the Magic: XY/XX | Sonic Team | Sega, Nintendo Australia | November 16, 2004 (NA) |
| Ferrari Challenge: Trofeo Pirelli | Climax | System 3 | July 4, 2008 (PAL) |
| FIFA 06 | Electronic Arts | Electronic Arts | September 30, 2005 (PAL) |
| FIFA 07 | EA Sports | EA Sports | September 29, 2006 (PAL) |
| FIFA 08 | EA Canada | EA Sports | September 28, 2007 (PAL) |
| FIFA 09 | EA Canada | EA Sports | October 3, 2008 (PAL) |
| FIFA 10 | EA Sports | Electronic Arts | October 1, 2009 (EU) |
| FIFA 11 | EA Sports | Electronic Arts | October 8, 2010 (NA,EU) |
| FIFA Street 2 | EA Canada | EA Sports BIG | February 28, 2006 (NA) |
| FIFA Street 3 | EA Sports, EA Canada | EA Sports | February 18, 2008 (NA) |
| Fifi & the Flowertots | Uacari | Avanquest | July 17, 2009 (EU) |
| Fighting Fantasy: The Warlock of Firetop Mountain | Big Blue Bubble | Aspyr | November 23, 2009 (NA) |
| Final Fantasy III | Matrix Software | Square Enix | August 24, 2006 (JP) |
| Final Fantasy IV | Matrix Software, Square Enix | Square Enix | December 20, 2007 (JP) |
| Final Fantasy XII Revenant Wings | Square Enix, Think & Feel Inc. | Square Enix | April 26, 2007 (JP) |
| Final Fantasy Crystal Chronicles: Echoes of Time | Square Enix | Square Enix | January 29, 2009 (JP) |
| Final Fantasy Crystal Chronicles: Ring of Fates | Square Enix | Square Enix | August 23, 2007 (JP) |
| Final Fantasy Fables: Chocobo Tales | h.a.n.d. | Square Enix | December 14, 2006 (JP) |
| Final Fantasy Tactics A2: Grimoire of the Rift | Square Enix | Square Enix | October 25, 2007 (JP) |
| Final Fantasy: The 4 Heroes of Light | Matrix Software | Square Enix | October 29, 2009 (JP) |
| Fire Emblem: Shadow Dragon | Intelligent Systems | Nintendo | August 7, 2008 (JP) |
| Fire Emblem: Shin Monshō no Nazo ~Hikari to Kage no Eiyū~ | Intelligent Systems | Nintendo | June 15, 2010 (JP) |
| Fish Tycoon | Big Fish Games, Last Day of Work | Eidos Interactive, Majesco Entertainment | October 16, 2007 (NA) |
| Fix It: Home Improvement | Oxygen Interactive | SouthPeak Games | May 21, 2010 (EU) |
| Fizz | DK Games | Lexicon Entertainment | February 29, 2008 (PAL) |
| Flash Focus: Vision Training in Minutes a Day | Namco Bandai Games, Nintendo | Nintendo | May 31, 2007 (JP) |
| Flipper Critters | Zen Studios | Conspiracy Entertainment, Ignition Entertainment | March 23, 2007 (PAL) |
| Florist Shop | Teyon | UFO Interactive Games, Rondomedia | September 21, 2010 (NA) |
| Flower, Sun, and Rain | h.a.n.d. | Marvelous Interactive, Rising Star Games, Xseed Games | March 6, 2008 (JP) |
| Flushed Away | Art | D3 Publisher | October 24, 2006 (NA) |
| Football Academy | EA Sports | EA Sports | March 29, 2009 (PAL) |
| Football Director DS | Sports Director Limited | Pinnacle | October 31, 2008 (PAL) |
| Ford Racing 3 | Visual Impact | Empire Interactive, Zoo Digital Publishing | December 7, 2005 (NA) |
| Fossil Fighters | Red Entertainment | Nintendo | April 17, 2008 (JP) |
| Fossil Fighters: Champions | Nintendo SPD, Red Entertainment, M2, Artdink | Nintendo | November 18, 2010 (JP) |
| Fossil League: Dino Tournament Challenge | MTO | D3 Publisher, MTO | August 25, 2005 (NA) |
| Foster's Home for Imaginary Friends: Imagination Invaders | Sensory Sweep Studios | Midway Games | November 12, 2007 (NA) |
| Franklin's Great Adventures | Neko Entertainment | The Game Factory | February 3, 2006 (PAL) |
| Freddi Fish And Friends: ABC Under The Sea | 1st Playable Productions | Atari | November 28, 2008 (EU) |
| Freedom Wings | Taito Corporation | Natsume, Taito Corporation, Zoo Digital Publishing | April 27, 2006 (JP) |
| Fresh Pretty Cure: Asobi Collection | Bandai | Namco Bandai Games | October 29, 2009 (JP) |
| Freshly-Picked Tingle's Rosy Rupeeland | Vanpool | Nintendo | September 2, 2006 (JP) |
| Frisbee Disc Freestyle / Frisbee Disc Golf | Destination Software | Destination Software | March 6, 2007 (NA) |
| Frogger: Helmet Chaos | Konami | Konami | September 27, 2005 (NA) |
| From the Abyss | Sonic Powered | Sonic Powered, Aksys Games | August 26, 2008 (NA) |
| Front Mission | Square Enix | Square Enix | March 22, 2007 (JP) |
| Front Mission 2089: Border of Madness | h.a.n.d. | Square Enix | May 29, 2008 (JP) |
| Fruits Mura no Doubutsu Tachi 2 | TDK Core | TDK Core | April 6, 2006 (JP) |
| Fullmetal Alchemist: Dual Sympathy | Bandai | Bandai, Destineer, Empire Interactive | July 21, 2005 (JP) |
| Fullmetal Alchemist: Trading Card Game | Destineer | Destineer | October 15, 2007 (NA) |
| Futari wa Pretty Cure: Max Heart - Danzen! DS de Precure - Chikara wo Awasete Dai Battle | Bandai | Namco Bandai Games | December 1, 2005 (JP) |
| Futari wa Pretty Cure Splash Star: Panpaka game deji kojo! | Bandai | Namco Bandai Games | November 30, 2006 (JP) |
| futureU | Aspyr Media | Aspyr Media | November 3, 2008 (NA) |
| Fuyu no Sonata DS | D3 Publisher | D3 Publisher | December 17, 2009 (JP) |
| G-Force | Keen Games | Disney Interactive Studios | July 21, 2009 (NA) |
| G.I. Joe: The Rise of Cobra | Backbone Entertainment | Electronic Arts | August 24, 2009 (NA) |
| Gachapin Challenge DS | Hudson Soft | Hudson Soft | July 17, 2008 (JP) |
| Gachapin Nikki DS | Hudson Soft | Hudson Soft | September 20, 2007 (JP) |
| Gakuen Alice | Kids Station | Kids Station | April 19, 2007 (JP) |
| The Gal Mahjong | D3 Publisher | D3 Publisher | September 25, 2008 (JP) |
| Galactik Football | 505 Games | 505 Games | July 1, 2009 (EU) |
| Galileo | D3 Publisher | D3 Publisher | October 16, 2008 (JP) |
| Game & Watch Collection | Nintendo | Nintendo | July 28, 2006 (JP) |
| Game & Watch Collection 2 | Nintendo | Nintendo | September 5, 2008 (JP) |
| Ganbare Goemon: Tōkai Dōchū Ōedo Tengu ri Kaeshi no Maki | Konami | Konami | June 23, 2005 (JP) |
| Ganbaru Watashi no Kakei Diary | Syn Sophia | Nintendo | July 12, 2007 (JP) |
| Gardening Mama | Cooking Mama Limited | Majesco Entertainment, Taito Corporation | March 19, 2009 (JP) |
| Garfield Gets Real | Gravity-i | Destination Software, Zoo Digital Publishing | November 15, 2007 (NA) |
| Garfield's Fun Fest | Black Lantern Studios | Destination Software, Zoo Digital Publishing | August 29, 2008 (PAL,NA) |
| Garfield's Nightmare | Shin'en | The Game Factory, Disney Interactive Studios | March 9, 2007 (PAL) |
| Garfield: A Tail of Two Kitties | Two Tribes B.V. | The Game Factory | August 25, 2006 (PAL) |
| The Gekai | D3 Publisher | D3 Publisher | August 28, 2008 (JP) |
| The Genshijin DS | D3 Publisher | D3 Publisher | March 27, 2008 (JP) |
| Generator Rex: Agent of Providence | Virtuos | Activision | November 1, 2011 (NA) |
| Geometry Wars: Galaxies | Kuju Entertainment | Sierra Entertainment | November 27, 2007 (NA) |
| George of the Jungle and the Search for the Secret | Crave Entertainment | Crave Entertainment, Ignition Entertainment | March 28, 2008 (PAL) |
| Ghostbusters: The Video Game | Zen Studios | Atari | June 16, 2009 (NA) |
| Ghost Trick: Phantom Detective | Capcom | Capcom | June 19, 2010 (JP) |
| Giana Sisters DS | Spellbound | DTP Entertainment | April 3, 2009 (EU) |
| Ginga Tetsudou 999 DS | Culture Brain | Culture Brain | October 14, 2010 (JP) |
| Gintama DS: Yorozuya Daisoudou | Namco Bandai Games | Namco Bandai Games | September 23, 2006 (JP) |
| Gintama Gintoki vs Hijikata | Banpresto | Banpresto | December 14, 2006 (JP) |
| Glory Days 2 | ODENIS Studios | Ghostlight, Secret Stash Games | August 6, 2007 (NA) |
| Glory of Heracles | Paon | Nintendo | May 22, 2008 (JP) |
| Go, Diego, Go!: Safari Rescue | Black Lantern Studios | 2K Play | November 5, 2007 (NA) |
| Go, Diego, Go!: Great Dinosaur Rescue | Black Lantern Studios | Take-Two Interactive | October 27, 2008 (NA) |
| Go West! A Lucky Luke Adventure | Neko Entertainment | Atari | November 20, 2007 (PAL) |
| Godzilla Unleashed: Double Smash | Santa Cruz Games | Atari | November 20, 2007 (NA) |
| Golden Balls | Mindscape | Mindscape | December 5, 2008 (EU) |
| The Golden Compass | Artificial Mind and Movement | Sega | November 30, 2007 (PAL) |
| Golden Nugget Casino DS | SkyRiver Studios | Majesco Entertainment | December 15, 2005 (NA) |
| Golden Sun: Dark Dawn | Camelot Software Planning | Nintendo | October 28, 2010 (JP) |
| GoldenEye: Rogue Agent | EA Tiburon, n-Space | EA Games | June 13, 2005 (NA) |
| Golgo 13: File G-13 o Oe | Marvelous Interactive | Marvelous Interactive | June 18, 2009 (JP) |
| Goosebumps HorrorLand | Scholastic Corporation | Scholastic Corporation | October 14, 2008 (NA) |
| GoPets: Vacation Island | 1st Playable Productions | Konami | March 18, 2008 (NA) |
| Gotouchi Kentei DS | Studio Zan | Spike | November 22, 2006 (JP) |
| Gourmet Chef | Ubisoft | Ubisoft | June 24, 2008 (NA) |
| Grand Theft Auto: Chinatown Wars | Rockstar Leeds | Rockstar Games, CyberFront | March 17, 2009 (NA) |
| Gravity Zero Racing | October 10, 2008 (PAL) | ||
| Green Lantern: Rise of the Manhunters | Griptonite Games | Warner Bros. Interactive Entertainment | June 7, 2011 (NA) |
| Greg Hastings Tournament Paintball MAX'D | The Whole Experience | Activision | January 31, 2006 (NA) |
| Grey's Anatomy: The Video Game | Longtail Studios | Ubisoft | March 4, 2009 (NA) |
| Guilty Gear Dust Strikers | Arc System Works | ASNetworks, Majesco Entertainment, THQ | April 25, 2006 (NA) |
| Guinness World Records: The Video Game | Warner Bros. Interactive Entertainment | Warner Bros. Interactive Entertainment | October 24, 2008 (PAL) |
| Guitar Hero: On Tour | Vicarious Visions | Activision | June 22, 2008 (NA) |
| Guitar Hero: On Tour Decades | Vicarious Visions | Activision | November 14, 2008 (PAL) |
| Guitar Hero: On Tour Modern Hits | Vicarious Visions | Activision | June 9, 2009 (NA) |
| Guitar Rock Tour | Ubisoft | Ubisoft | November 4, 2008 (NA) |
| Gunpey DS | Art | Atari, Namco Bandai Games | October 19, 2006 (JP) |
| The Haioku Byoutou | D3 Publisher | D3 Publisher | July 10, 2008 (JP) |
| The Haishasan | D3 Publisher | D3 Publisher | March 13, 2008 (JP) |
| Habu Yoshiharu Shōgi de Kitaeru: Ketsudanryoku DS | Ides | Ides | March 12, 2009 (JP) |
| Hajime no Ippo The Fighting! DS | Entertainment Software Publishing | Entertainment Software Publishing | December 4, 2008 (JP) |
| Hakuōki DS | Idea Factory | Idea Factory | December 1, 2009 (JP) |
| Hakuōki Yuugiroku DS | Idea Factory | Idea Factory | April 28, 2011 (JP) |
| Hakuōki Zuisōroku DS | Idea Factory | Idea Factory | February 17, 2011 (JP) |
| Hamsterz Life | MTO, Digital Kids | Digital Kids, Ubisoft | November 28, 2006 (NA) |
| Hana Yori Dango: Koi Seyo Otome | Konami | Konami | July 10, 2008 (JP) |
| Hands On! Tangrams | Island Officials | Storm City Games | October 6, 2009 (NA) |
| Hannah Montana | DC Studios | Buena Vista Games, Disney Interactive Studios | October 9, 2006 (PAL,NA) |
| Hannah Montana: Music Jam | Gorilla Systems | Disney Interactive Studios | October 16, 2007 (NA) |
| Hannah Montana: The Movie | n-Space | Disney Interactive Studios | April 7, 2009 (NA) |
| Hanshin Tigers DS | Spike | Spike | August 28, 2008 (JP) |
| Happy Feet | Artificial Mind and Movement | Midway Games, Warner Bros. Interactive Entertainment | November 14, 2006 (NA) |
| Happy Feet Two | WayForward Technologies | Warner Bros. Interactive Entertainment | November 8, 2011 (NA) |
| Happy Happy Clover | TDK Core | TDK Core | February 14, 2008 (JP) |
| Happy Hippos On Tour | 10tacle Studios | 10tacle Studios | November 12, 2007 (EU) |
| Hardy Boys: Treasure on the Track | XPEC Entertainment | DreamCatcher Games | September 1, 2009 (NA) |
| Harlem Globetrotters: World Tour | Destination Software | Destination Software, Zoo Digital Publishing | November 24, 2006 (PAL) |
| Harobots Action! | Sunrise Interactive | Sunrise Interactive | December 29, 2005 (JP) |
| Harry Potter and the Goblet of Fire | Electronic Arts | Electronic Arts | November 8, 2005 (NA) |
| Harry Potter and the Half-Blood Prince | EA Bright Light Studio | EA Games | June 30, 2009 (NA) |
| Harry Potter and the Order of the Phoenix | EA Games | EA Games | June 25, 2007 (NA) |
| Harry Potter and the Deathly Hallows, Part 1 | EA Bright Light Studio | EA Games | November 16, 2010 (NA) |
| Harry Potter and the Deathly Hallows, Part 2 | EA Bright Light Studio | EA Games | July 12, 2011 (NA) |
| Harvest Moon DS | Marvelous Interactive | Marvelous Interactive, Natsume, Rising Star Games | March 17, 2005 (JP) |
| Harvest Moon DS Cute | Marvelous Interactive | Marvelous Interactive, Natsume | December 8, 2005 (JP) |
| Harvest Moon: Frantic Farming | Platinum-Egg | Natsume | May 29, 2009 (NA) |
| Harvest Moon DS: Island of Happiness | Marvelous Interactive | Marvelous Interactive, Natsume, Rising Star Games | February 1, 2007 (JP) |
| Harvest Moon DS: Sunshine Islands | Marvelous Interactive | Marvelous Interactive | February 21, 2008 (JP) |
| Hayate no Gotoku!: Boku ga Romeo de Romeo ga Boku de | HuneX | Konami | August 23, 2007 (JP) |
| Hayate no Gotoku!: Ojō-sama Produce Daisakusen Bokuiro ni Somare! | HuneX | Konami | March 14, 2008 (JP) |
| HeartCatch PreCure! Oshare Collection | Bandai | Namco Bandai Games | August 5, 2010 (JP) |
| Heavy Armor Brigade | Milestone | Milestone, UFO Interactive Games | November 29, 2007 (JP) |
| Hell's Kitchen | Ludia Inc. | Ubisoft | September 9, 2008 (NA) |
| Hello Kitty Daily | Dorasu | Aspyr Media | October 27, 2008 (NA) |
| Hello Kitty: Big City Dreams | Empire Interactive | Atari, Empire Interactive | October 14, 2008 (NA) |
| Hello Pocoyo! | Zinkia | Virgin Play | November 11, 2008 (PAL) |
| Henry Hatsworth in the Puzzling Adventure | EA Tiburon | Electronic Arts | March 17, 2009 (NA) |
| Heracles: Battle With The Gods | Midas Interactive Entertainment | Conspiracy Entertainment, Midas Interactive Entertainment | November 2, 2007 (PAL) |
| Hercules no Eikō: Tamashii no Shōmei | Paon | Nintendo | May 22, 2008 (JP) |
| Heroes of Mana | Brownie Brown | Square Enix | March 8, 2007 (JP) |
| Hi Hamtaro! Little Hamsters Big Adventure | AlphaDream | 505 Games, Marvelous Interactive, Natsume | March 15, 2007 (JP) |
| Hi Hi Puffy AmiYumi: The Genie and the Amp | Sensory Sweep Studios | D3 Publisher | June 27, 2006 (NA) |
| High School Musical: Makin' the Cut! | Artificial Mind and Movement | Buena Vista Games | August 14, 2007 (NA) |
| High School Musical 2: Work This Out! | Artificial Mind and Movement | Disney Interactive Studios | April 15, 2008 (NA) |
| High School Musical 3: Senior Year | Griptonite Games | Disney Interactive Studios | October 21, 2008 (NA) |
| Higurashi no Naku Koro ni Kizuna: Daiichikan Tatari | Alchemist | Alchemist | June 26, 2008 (JP) |
| Higurashi no Naku Koro ni Kizuna: Dainikan Sō | Alchemist | Alchemist | November 27, 2008 (JP) |
| Higurashi no Naku Koro ni Kizuna: Daisankan Rasen | Alchemist | Alchemist | May 28, 2009 (JP) |
| Higurashi no Naku Koro ni Kizuna: Daiyonkan Kizuna | Alchemist | Alchemist | February 25, 2010 (JP) |
| Hiiro no Kakera DS | Idea Factory | Idea Factory | May 22, 2008 (JP) |
| Hirameki Action: Chibikko Wagan no Daiki na Bouken | Namco Bandai Games | Namco Bandai Games | January 29, 2009 (JP) |
| Hitman Reborn! DS: Mafia Daishūgō Vongola Festival! | Takara Tomy | Takara Tomy | December 4, 2008 (JP) |
| Holly Hobbie & Friends | FrontLine Studios | Eidos Interactive, Majesco Entertainment | October 8, 2007 (NA) |
| Homie Rollerz | Webfoot Technologies | Destineer | March 5, 2008 (NA) |
| Honeycomb Beat | Hudson Soft | Hudson Soft, Konami | August 10, 2006 (JP) |
| Horrible Histories: Ruthless Romans | Virtual Identity | Slitherline Software | August 7, 2009 (EU) |
| Horrid Henry | Asylum Entertainment | SouthPeak Games | March 26, 2010 (EU) |
| Horse Life | Neko Entertainment | 505 Games, D3 Publisher | October 12, 2007 (PAL) |
| Horsez | MTO | MT, Ubisoft | November 28, 2006 (NA) |
| Hoshigami Remix | Arc System Works | 505 Games, Aksys Games, ASNetworks | May 24, 2007 (JP) |
| Hoshizora no Comic Garden | HuneX | D3 Publisher | September 11, 2008 (JP) |
| Hot Wheels: Beat That! | Human Soft | Activision | November 6, 2007 (NA) |
| Hotel Dusk: Room 215 | Cing | Nintendo | January 22, 2007 (NA) |
| Hotel for Dogs | 505 Games | 505 Games | January 6, 2009 (NA) |
| Hotel Giant 2 | Creative Pattern | Nobilis | November 11, 2008 (NA) |
| Hotel Giant DS | Enlight Software | Nobilis | November 11, 2008 (NA) |
| The Humans | Blue Monkey Studios | Deep Silver | November 11, 2008 (NA) |
| Hurry Up Hedgehog! | Ivolgamus | Oxygen Games | March 28, 2008 (PAL) |
| Hysteria Hospital: Emergency Ward | Gameinvest | Oxygen Games | June 16, 2009 (NA) |
| I Heart Geeks! | December 20, 2011 (NA) | ||
| I Love Dolphin | August 9, 2007 (JP) | ||
| I Spy: Fun House | Big Blue Bubble | Scholastic Corporation, Deep Silver | August 29, 2007 (NA) |
| iCarly | Activision | Activision | October 23, 2009 (NA) |
| Ice Age 2: The Meltdown | Amaze Entertainment | Sierra Entertainment, Vivendi Games | March 14, 2006 (NA) |
| Ice Age: Continental Drift - Arctic Games | Behaviour Interactive | Activision | June 29, 2012 (EU) |
| Ice Age: Dawn of the Dinosaurs | Eurocom | Activision | June 30, 2009 (NA) |
| Idaten Jump DS: Moero! Flame Kaiser | Taito Corporation | Taito Corporation | September 7, 2006 (JP) |
| Igor | Santa Cruz Games | Legacy Interactive | September 11, 2008 (NA) |
| IL-2 Sturmovik: Birds of Prey | DiP Interactive | 1C Company, 505 Games | September 3, 2009 (AU) |
| Illust Logic DS + Colorful Logic | Hudson Soft | Hudson Soft | October 25, 2007 (JP) |
| The Illust Puzzle & Suuji Puzzle 2 | D3 Publisher | D3 Publisher | November 29, 2007 (JP) |
| Imagine: Animal Doctor | Ubisoft | Ubisoft | October 23, 2007 (NA) |
| Imagine: Artist | Ubisoft | Ubisoft | October 27, 2009 (NA) |
| Imagine: Babies | Ubisoft | Ubisoft | October 23, 2007 (NA) |
| Imagine: Baby Club | Ubisoft | Ubisoft | September 19, 2008 (EU) |
| Imagine: Ballet Star | Ubisoft | Ubisoft | November 18, 2008 (NA) |
| Imagine: Boutique Owner | Ubisoft | Ubisoft | June 2, 2009 (NA) |
| Imagine: Champion Rider | Ubisoft | Ubisoft | October 10, 2008 (EU) |
| Imagine: Cheerleader | 1st Playable Productions | Ubisoft | January 27, 2009 (NA) |
| Imagine: Detective | Ubisoft | Ubisoft | September 8, 2009 (NA) |
| Imagine: Family Doctor | Wizarbox | Ubisoft | March 31, 2009 (NA) |
| Imagine: Fashion Designer | Ubisoft | Ubisoft | October 23, 2007 (NA) |
| Imagine: Fashion Designer New York | Virtual Toys, Lexis Numerique | Ubisoft | September 19, 2008 (EU) |
| Imagine: Fashion Designer World Tour | Virtual Toys | Ubisoft | October 20, 2009 (NA) |
| Imagine: Figure Skater | Ubisoft Paris | Ubisoft, Spike | March 15, 2007 (JP) |
| Imagine: Gymnast | Ubisoft | Ubisoft | November 27, 2008 (JP) |
| Imagine: Ice Champions | Ubisoft | Spike, Ubisoft | December 13, 2007 (JP) |
| Imagine: Interior Designer | Ubisoft | Ubisoft | November 4, 2008 (NA) |
| Imagine: Makeup Artist | Ubisoft | Ubisoft | July 10, 2008 (JP) |
| Imagine: Master Chef | Ubisoft | Ubisoft | September 14, 2007 (PAL) |
| Imagine: Modern Dancer | Ubisoft | Ubisoft | September 19, 2008 (EU) |
| Imagine: Movie Star | Powerhead Games, Ubisoft | Ubisoft | November 18, 2008 (NA) |
| Imagine: Music Fest | Ubisoft | Ubisoft | May 5, 2009 (NA) |
| Imagine: Rock Star | Gevo Entertainment | Ubisoft | June 17, 2008 (PAL) |
| Imagine: Salon Stylist | Ubisoft | Ubisoft | September 29, 2009 (NA) |
| Imagine: Soccer Captain | Ubisoft | Ubisoft | August 11, 2009 (NA) |
| Imagine: Teacher | Magic Pockets | Ubisoft | August 12, 2008 (NA) |
| Imagine: Teacher Class Trip | Ubisoft | Ubisoft | August 25, 2009 (NA) |
| Imagine: Wedding Designer | Lexis Numerique, Ubisoft, Virtual Toys | Ubisoft | November 11, 2008 (NA) |
| Impossible Mission | System 3 | Play It!, System 3, Warner Bros. Interactive Entertainment | August 31, 2007 (JP) |
| Inazuma Eleven | Level-5 | Level-5 | August 22, 2008 (JP) |
| Inazuma Eleven 2 Kyoui no Shinryakusha | Level-5 | Level-5 | October 1, 2009 (JP) |
| Inazuma Eleven 3 Sekai e no Chousen | Level-5 | Level-5 | December 16, 2010 (JP) |
| The Incredible Hulk | Amaze Entertainment | Sega | June 5, 2008 (NA) |
| Disney/Pixar's The Incredibles: Rise of the Underminer | Helixe | Sega, THQ | November 1, 2005 (NA) |
| Indiana Jones and the Staff of Kings | LucasArts | Activision, LucasArts | June 9, 2009 (NA) |
| Indianapolis 500 Legends | Torus Games | Destineer | December 19, 2007 (NA) |
| Infinite Space | Nude Maker, PlatinumGames | Sega | June 11, 2009 (JP) |
| Inkheart | DreamCatcher Games | The Adventure Company | January 12, 2009 (NA) |
| Insecticide | Crackpot Entertainment, Creat Studios | Gamecock Media Group | March 11, 2008 (NA) |
| Interactive Storybook Series 1 | Tommo | Tommo | September 18, 2007 (NA) |
| Interactive Storybook Series 2 | Tommo | Tommo | October 26, 2007 (NA) |
| Interactive Storybook Series 3 | Tommo | Tommo | October 26, 2007 (NA) |
| International Athletics | Code Monkeys | Ghostlight | September 25, 2008 (AU) |
| InuYasha: Secret of the Divine Jewel | Namco Bandai Games | Namco Bandai Games | January 23, 2007 (NA) |
| Iron Chef America: Supreme Cuisine | Black Lantern Studios | Destineer | October 21, 2008 (NA) |
| Iron Feather | Konami | Konami | January 19, 2006 (JP) |
| Iron Man | Artificial Mind and Movement | Sega | May 2, 2008 (PAL,NA) |
| Iron Man 2 | Sega | Sega | April 29, 2010 (AU) |
| Irozuki Tincle no Koi no Balloon Trip | Vanpool | Nintendo | August 6, 2009 (JP) |
| Itadaki Street DS | Armor Project | Square Enix | June 21, 2007 (JP) |
| Ivy the Kiwi? | Prope | Namco Bandai Games, Xseed Games, Rising Star Games | April 22, 2010 (JP) |
| Izuna: Legend of the Unemployed Ninja | Ninja Studio | 505 Games, Atlus, Success | June 8, 2006 (JP) |
| Izuna 2: The Unemployed Ninja Returns | Ninja Studio, Success | Atlus, Success | November 29, 2007 (JP) |
| Jackass: The Game | Sensory Sweep Studios | Empire Interactive, Red Mile Entertainment | October 2, 2007 (NA) |
| Jagged Alliance DS | Strategy First, Cypron Studios | Atari | October 28, 2008 (NA) |
| Jake Hunter Detective Story: Memories of the Past | WorkJam | Aksys Games | July 19, 2007 (JP) |
| Jake Hunter: Detective Chronicles | WorkJam | Arc System Works, Aksys Games | July 19, 2007 (JP) |
| Jake Power: Handyman | Ubisoft | Ubisoft | November 21, 2008 (EU) |
| Jake Power: Policeman | Ubisoft | Ubisoft | November 21, 2008 (EU) |
| Jam Sessions | Plato | Plato, Ubisoft | February 1, 2007 (JP) |
| Jam Sessions 2 | Plato | Plato, Ubisoft | October 20, 2009 (NA) |
| Jam with the Band | Nintendo | Nintendo | June 26, 2008 (JP) |
| Jambo! Safari: Animal Rescue | Sega | Sega | November 17, 2009 (NA) |
| James Cameron's Avatar: The Game | Ubisoft | Ubisoft | December 1, 2009 (NA) |
| James Pond: RoboCod | Creature Labs | Play It!, Codemasters | December 8, 2005 (PAL) |
| Jenga World Tour | Atomic Planet Entertainment | Atari | November 13, 2007 (NA) |
| Jet Impulse | Nintendo | Nintendo | February 8, 2007 (JP) |
| Jetix Puzzle Buzzle | Blast! Entertainment | Blast! Entertainment | April 4, 2008 (PAL) |
| Jewel Quest Solitaire | Avanquest | Global Software Publishing | April 9, 2009 (EU) |
| Jewel Quest: Expeditions | iWin | Activision Value | September 18, 2007 (NA) |
| The Jidousha Kyoushuusho DS | D3 Publisher | D3 Publisher | May 31, 2007 (JP) |
| Jigoku Shōjo Akekazura | Compile Heart | Compile Heart | September 27, 2007 (JP) |
| Jigway Puzzle | Hudson Soft | Hudson Soft | March 6, 2008 (JP) |
| Jillian Michaels' Fitness Ultimatum 2010 | 3G Studios | Majesco Entertainment | October 20, 2009 (NA) |
| Jinsei Game DS | Atlus | Atlus | July 27, 2006 (JP) |
| Jissen Pachi-Slot Hisshōhō! Hokuto no Ken | Sammy Studios | Sammy Studios | June 4, 2005 (JP) |
| John Deere: Harvest in the Heartland | Black Lantern Studios | Destineer, Ubisoft | November 20, 2007 (NA) |
| Jojo's Fashion Show | GameLab | Ubisoft | January 27, 2009 (NA) |
| Jonas | Altron | Disney Interactive Studios | November 10, 2009 (NA) |
| Journey to the Center of the Earth | Human Soft | THQ | June 27, 2008 (PAL) |
| Juggler DS | Commonseed | Commonseed | November 13, 2008 (JP) |
| Juiced 2: Hot Import Nights | Juice Games | THQ | September 17, 2007 (NA) |
| Jump Super Stars | Ganbarion | Nintendo, Tommo | August 8, 2005 (JP) |
| Jump Ultimate Stars | Ganbarion | Nintendo, Tommo | November 23, 2006 (JP) |
| Justice League Heroes | Sensory Sweep Studios | Eidos Interactive, Warner Bros. Interactive Entertainment | October 17, 2006 (NA) |
| K-1 World GP | D3 Publisher | D3 Publisher | December 6, 2007 (JP) |
| Kabu Trader Shun | Capcom | Capcom | June 7, 2007 (JP) |
| Kachō Shima Kōsaku DS: Dekiru Otoko no Love & Success | Konami | Konami | March 19, 2008 (JP) |
| Kamen Rider Battle Ganbaride: Card Battle Taisen | Natsume | Bandai | July 29, 2010 (JP) |
| Kamen Rider: Dragon Knight | Natsume | D3 Publisher | November 17, 2009 (NA) |
| Kanji Sonomama Rakubiki Jiten | Nintendo | Nintendo | April 13, 2006 (JP) |
| The Kanshikikan 2 | D3 Publisher | D3 Publisher | May 31, 2007 (JP) |
| The Kanshikikan | D3 Publisher | D3 Publisher | February 17, 2005 (JP) |
| Kanshū Nippon Jōshikiryoku Kentei Kyōkai: Imasara Hito ni wa Kikenai Otona no Jōshikiryoku Training DS | HAL Laboratory | Nintendo | October 26, 2006 (JP) |
| Katekyo Hitman Reborn! DS - Shinuki Max! Vongola Carnival!! | Takara Tomy | Takara Tomy | March 29, 2007 (JP) |
| Katekyo Hitman Reborn DS: Fate of Heat | Takara Tomy | Takara Tomy | May 1, 2008 (JP) |
| Katekyo Hitman Reborn! DS Flame Rumble X | Takara Tomy | Takara Tomy | July 23, 2009 (JP) |
| Kemeko Deluxe! DS: Yome to Meka to Otoko to Onna | 5pb., Suzak | Genterprise | February 26, 2009 (JP) |
| Kenshūi Tendo Doctor | Spike | Spike | December 2, 2004 (JP) |
| Ketsui Death Label | Cave | Arika | October 23, 2008 (JP) |
| Kim Possible: Kimmunicator | Artificial Mind and Movement | Buena Vista Games | November 9, 2005 (NA) |
| Kimi no Yusha | SNK Playmore | SNK Playmore | October 23, 2008 (JP) |
| King of Clubs | Oxygen Games | Oxygen Games | July 25, 2008 (PAL) |
| Kingdom Hearts 358/2 Days | h.a.n.d. | Square Enix | May 30, 2009 (JP) |
| Kingdom Hearts Re:coded | h.a.n.d. | Square Enix | October 7, 2010 (JP) |
| Kira Kira Pop Princess | Dimple Entertainment | 505 Games, Dimple Entertainment | October 26, 2006 (JP) |
| Kirby Mass Attack | HAL Laboratory | Nintendo | August 4, 2011 (JP) |
| Kirby Super Star Ultra | HAL Laboratory | Nintendo | September 22, 2008 (NA) |
| Kirby: Squeak Squad | Flagship, HAL Laboratory | Nintendo | November 2, 2006 (JP) |
| Kirby: Canvas Curse | HAL Laboratory | Nintendo | March 24, 2005 (JP) |
| Knights in the Nightmare | Sting Entertainment | Atlus, Sting Entertainment | September 25, 2008 (JP) |
| Koe de Asobou! HeartCatch PreCure! | Bandai | Namco Bandai Games | November 11, 2010 (JP) |
| Konami Classics Series: Arcade Hits | Konami | Konami | March 15, 2007 (JP) |
| Konductra | oeFun | O3 Entertainment | October 31, 2006 (NA) |
| KORG DS-10 | Cavia | AQ Interactive, Nintendo Australia, Xseed Games | July 24, 2008 (JP) |
| KORG DS-10 Plus | Cavia | AQ Interactive, Xseed Games | September 17, 2009 (JP) |
| Kotoba no Puzzle: Mojipittan DS | Namco Bandai Games | Namco Bandai Games | March 15, 2007 (JP) |
| The Koushounin | D3 Publisher | D3 Publisher | October 25, 2007 (JP) |
| Kousoku Card Battle: Card Hero | Intelligent Systems | Nintendo | December 20, 2007 (JP) |
| Kung Fu Panda | Vicarious Visions | Activision | June 3, 2008 (NA) |
| Kung Fu Panda: Legendary Warriors | Artificial Mind and Movement | Activision | November 8, 2008 (NA) |
| Kurikin Nano Island Story | MediaKite | Nintendo | May 24, 2007 (JP) |
| Kurupoto Cool Cool Stars | Starfish SD | Starfish SD, UFO Interactive Games | March 15, 2007 (NA) |
| L the Prologue to Death Note -Rasen no Wana- | Konami | Konami | February 7, 2008 (JP) |
| Labyrinth | Lancarse | 505 Games, Taito Corporation, UFO Interactive Games | December 1, 2005 (NA) |
| Last King of Africa | Focus Home Interactive | Focus Home Interactive | November 11, 2008 (NA) |
| Last Window: The Secret of Cape West | Cing | Nintendo | January 14, 2010 (JP) |
| Learn to Play Chess with Fritz and Chesster | Deep Silver | Deep Silver | February 6, 2009 (EU) |
| Learn with Pokémon: Typing Adventure | Genius Sonority | Nintendo | April 21, 2011 (JP) |
| Left Brain Right Brain | Japan Art Media | 505 Games, Majesco Entertainment | November 16, 2007 (EU) |
| Legacy of Ys: Books I & II | Interchannel | Atlus | February 24, 2009 (NA) |
| The Legend of Kage 2 | Taito Corporation | Square Enix, Taito Corporation, Ubisoft | March 11, 2008 (JP) |
| Legend of Kay | JoWooD Productions | DreamCatcher Games | May 28, 2010 (EU) |
| The Legend of Spyro: A New Beginning | Amaze Entertainment | Sierra Entertainment | October 17, 2006 (NA) |
| The Legend of Spyro: Dawn of the Dragon | Tantalus Media | Sierra Entertainment | October 21, 2008 (NA) |
| The Legend of Spyro: The Eternal Night | The Fizz Factor | Sierra Entertainment | October 2, 2007 (NA) |
| The Legend of Zelda: Phantom Hourglass | Nintendo EAD | Nintendo | June 23, 2007 (JP) |
| The Legend of Zelda: Spirit Tracks | Nintendo EAD | Nintendo | December 7, 2009 (NA) |
| The Legendary Starfy | Tose Co., Ltd. | Nintendo | July 10, 2008 (JP) |
| Lego Batman: The Video Game | TT Fusion | Warner Bros. Interactive Entertainment, DC Comics | September 23, 2008 (NA) |
| Lego Batman 2: DC Super Heroes | Traveller's Tales | Warner Bros. Interactive Entertainment | June 19, 2012 (NA) |
| Lego Battles | Hellbent Games | Warner Bros. Interactive Entertainment | June 9, 2009 (NA) |
| Lego Battles: Ninjago | Hellbent Games, Traveller's Tales | Warner Bros. Interactive Entertainment | April 12, 2011 (NA) |
| Lego Friends | Hellbent Games | Warner Bros. Interactive Entertainment | December 12, 2013 (NA) |
| Lego Harry Potter: Years 1-4 | Traveller's Tales | Warner Bros. Interactive Entertainment | November 11, 2010 (NA) |
| Lego Harry Potter: Years 5-7 | Traveller's Tales | Warner Bros. Interactive Entertainment | November 11, 2011 (NA) |
| Lego Indiana Jones: The Original Adventures | Traveller's Tales | Activision, LucasArts | June 3, 2008 (NA) |
| Lego Indiana Jones 2: The Adventure Continues | Traveller's Tales | LucasArts | November 17, 2009 (NA) |
| Lego Legends of Chima: Laval's Journey | TT Games | Warner Bros. Interactive Entertainment | August 31, 2013 (NA) |
| Lego The Lord of the Rings | Traveller's Tales | Warner Bros. Interactive Entertainment | October 30, 2012 (NA) |
| Lego Marvel Super Heroes: Universe in Peril | TT Games | Warner Bros. Interactive Entertainment | February 18, 2014 (NA) |
| Lego Pirates of the Caribbean: The Video Game | Traveller's Tales | Disney Interactive Studios | May 10, 2011 (NA) |
| Lego Rock Band | Backbone Entertainment | Warner Bros. Interactive Entertainment | November 3, 2009 (NA) |
| Lego Star Wars: The Complete Saga | Traveller's Tales | LucasArts | November 6, 2007 (NA) |
| Lego Star Wars II: The Original Trilogy | Amaze Entertainment | Electronic Arts, LucasArts | September 11, 2006 (PAL) |
| Lego Star Wars III: The Clone Wars | Traveller's Tales | LucasArts | March 22, 2011 (NA) |
| Let's Pilates | Vanpool | Konami | December 20, 2007 (JP) |
| Let's Play Fashion Designer | Deep Silver | Deep Silver | December 5, 2008 (PAL) |
| Let's Play Firemen | Deep Silver | Deep Silver | February 27, 2009 (PAL) |
| Let's Play Mums | Deep Silver | Deep Silver | December 5, 2008 (PAL) |
| Let's Play Pet Hospitals | Biodroid Productions | Deep Silver | February 27, 2009 (PAL) |
| Let's Play Schools | ZigZag Island | Deep Silver | December 5, 2008 (PAL) |
| Let's Play Shops | Deep Silver | Deep Silver | December 5, 2008 (PAL) |
| Let's Ride: Friends Forever | THQ | THQ | March 3, 2008 (NA) |
| Let's Yoga | Vanpool | Konami | July 5, 2007 (JP) |
| LifeSigns: Surgical Unit | Spike | DreamCatcher Games, JoWooD Productions, Spike | October 21, 2005 (JP) |
| Line Rider 2: Unbound | inXile Entertainment | Deep Silver, Genius Products | September 16, 2008 (NA) |
| Lionel Trains: On Track | Black Lantern Studios | Destination Software | December 6, 2006 (NA) |
| Lise no Atelier: Ordre no Renkinjutsushi | Gust | Gust | April 19, 2007 (JP) |
| Little League World Series Baseball 2008 | Activision | Activision | August 5, 2008 (NA) |
| Little Red Riding Hood's Zombie BBQ | EnjoyUp | Destineer | October 28, 2008 (PAL,NA) |
| Littlest Pet Shop | October 14, 2008 (NA) | ||
| Littlest Pet Shop: Garden | Electronic Arts | Electronic Arts | October 14, 2008 (NA) |
| Littlest Pet Shop: Jungle | Electronic Arts | Electronic Arts | October 14, 2008 (NA) |
| Littlest Pet Shop: Winter | Electronic Arts | Electronic Arts | October 14, 2008 (NA) |
| Lock's Quest | 5th Cell | THQ | September 8, 2008 (NA) |
| Lode Runner | Hudson Soft | Hudson Soft | October 26, 2006 (JP) |
| LOL | Route24 | Agetec, Rising Star Games, skip Ltd. | July 19, 2007 (JP) |
| Lola & Virginia | Imira Entertainment | Virgin Play | November 11, 2008 (PAL) |
| Londonian Gothics: Mekyū no Lolita | Megacyber | Megacyber | October 13, 2005 (JP) |
| Looney Tunes: Cartoon Conductor | Amaze Entertainment | Eidos Interactive | June 6, 2008 (PAL) |
| Looney Tunes: Duck Amuck | WayForward Technologies | Warner Bros. Interactive Entertainment | October 9, 2007 (NA) |
| The Lord of the Rings: Aragorn's Quest | TT Fusion | Warner Bros. Interactive Entertainment | September 14, 2010 (NA) |
| The Lord of the Rings: Conquest | Artificial Mind and Movement | Electronic Arts | January 9, 2009 (PAL) |
| Lost in Blue | Konami | Konami | August 25, 2005 (JP) |
| Lost in Blue 2 | Konami | Konami | March 15, 2007 (JP) |
| Lost in Blue 3 | Konami | Konami | December 20, 2007 (JP) |
| LostMagic | Taito Corporation | Taito Corporation, Ubisoft | January 19, 2006 (JP) |
| Love Cat Life | Interchannel | Interchannel | August 30, 2007 (JP) |
| LovePlus | Konami | Konami | September 3, 2009 (JP) |
| LovePlus+ | Konami | Konami | June 24, 2010 (JP) |
| Lucky Star Moe Drill | Kadokawa Shoten | Kadokawa Shoten | December 1, 2005 (JP) |
| Luminator DS | VIS Entertainment | Xider Games | November 11, 2008 (PAL) |
| Luminous Arc | Imageepoch | Atlus, Marvelous Entertainment, Rising Star Games | February 8, 2007 (JP) |
| Luminous Arc 2 | Imageepoch | Atlus, Marvelous Entertainment | May 15, 2008 (JP) |
| Luminous Arc 3 | Imageepoch | Marvelous Entertainment | December 10, 2009 (JP) |
| Lunar Knights | Kojima Productions | Konami | February 6, 2007 (NA) |
| Lunar: Dragon Song | Game Arts, Japan Art Media | Marvelous Entertainment, Rising Star Games, Ubisoft | August 25, 2005 (JP) |
| Lupin Sansei: Shijou Saidai no Zunousen | Nex Entertainment | Namco Bandai Games | February 11, 2010 (JP) |
| Lux-Pain | Killaware | Ignition Entertainment, Marvelous Entertainment, Rising Star Games | March 27, 2008 (JP) |
| Luxor: Pharaoh's Challenge | Mac Play | MumboJumbo | December 18, 2007 (NA) |
| M&M's Adventure | Nikitova Games | Destination Software | November 21, 2008 (NA) |
| M&M's Break' Em | Destination Software | Destination Software, Zoo Digital Publishing | March 25, 2007 (NA) |
| M&M's Kart Racing | FrontLine Studios | Destination Software, Zoo Digital Publishing | March 24, 2008 (NA) |
| Mabeop Cheonjamun DS | Skonec | Nintendo of Korea | April 16, 2009 (KR) |
| Mabeop Cheonjamun DS 2: The Final Hanja Magic | Skonec | Nintendo of Korea | January 27, 2011 (KR) |
| Madagascar | Vicarious Visions | Activision, Bandai | May 23, 2005 (NA) |
| Madagascar: Escape 2 Africa | Amaze Entertainment | Activision | November 4, 2008 (NA) |
| Madagascar Kartz | Sidhe | Activision | October 23, 2009 (NA) |
| Madden NFL 2005 | EA Tiburon | EA Sports | November 17, 2004 (NA) |
| Madden NFL 06 | EA Sports | EA Sports | August 8, 2005 (NA) |
| Madden NFL 07 | Exient Entertainment | EA Sports | August 22, 2006 (NA) |
| Madden NFL 08 | EA Tiburon | EA Sports | August 14, 2007 (NA) |
| Madden NFL 09 | EA Tiburon | EA Sports | August 12, 2008 (NA) |
| Mage Knight: Destiny's Soldier | Big Blue Bubble | Namco Bandai Games | September 26, 2006 (NA) |
| The Magic School Bus: Oceans | Big Blue Bubble | Scholastic | October 25, 2011 (NA) |
| Magical Starsign | Brownie Brown | Nintendo | June 22, 2006 (JP) |
| Magical Zunou Power!! | D3 Publisher | D3 Publisher | December 25, 2008 (JP) |
| Magician's Quest: Mysterious Times | Konami | Konami | November 12, 2008 (JP) |
| Magnetica | Mitchell Corporation | Nintendo | March 2, 2006 (JP) |
| Mah Jong Quest: Expeditions | Game Brains | Activision, Global Software Publishing | October 16, 2007 (NA) |
| The Mahjong | D3 Publisher | D3 Publisher | June 30, 2005 (JP) |
| Mahjong Taikai | Koei | Koei | December 2, 2004 (JP) |
| Mainichi Suteki! Hello Kitty no Life Kit | Dorart | Dorart | September 13, 2007 (JP) |
| Majin Tantei Nōgami Neuro: Neuro to Miko no Bishoku Sanmai | Marvelous Entertainment | Marvelous Entertainment | June 12, 2008 (JP) |
| Majime ni Fumajime Kaiketsu Zorori - Kyoufu no Takarabako | August 31, 2006 (JP) | ||
| Major DS: Dream Baseball | Takara Tomy | Takara Tomy | July 31, 2008 (JP) |
| Major League Baseball 2K7 | Skyworks Technologies | 2K Sports | March 19, 2007 (NA) |
| Major League Baseball 2K8 Fantasy All-Stars | Deep Fried Entertainment | 2K Sports | April 14, 2008 (NA) |
| Major League Baseball 2K9 Fantasy All-Stars | Deep Fried Entertainment | 2K Sports | March 3, 2009 (NA) |
| Make 10: A Journey of Numbers | MuuMuu | Nintendo | October 10, 2007 (JP) |
| MapleStory DS | Nexon | Nexon | April 15, 2010 (KR) |
| March of the Penguins | Destination Software | Destination Software, Zoo Digital Publishing | November 27, 2006 (NA) |
| Margot's Word Brain | Slam Games Limited | Zoo Games | September 23, 2008 (NA) |
| Margot's Word Play | Slam Games | Zoo Games | July 18, 2008 (PAL) |
| Mario & Luigi: Bowser's Inside Story | AlphaDream | Nintendo | February 11, 2009 (JP) |
| Mario & Luigi: Partners in Time | AlphaDream | Nintendo | November 28, 2005 (NA) |
| Mario & Sonic at the Olympic Games | Sega | Nintendo, Sega | January 17, 2008 (JP) |
| Mario & Sonic at the Olympic Winter Games | Sega | Nintendo, Sega | October 13, 2009 (NA) |
| Mario Hoops 3-on-3 | Square Enix | Nintendo | July 27, 2006 (JP) |
| Mario Kart DS | Nintendo | Nintendo | November 14, 2005 (NA) |
| Mario Party DS | Hudson Soft | Nintendo | November 8, 2007 (JP) |
| Mario vs. Donkey Kong: Mini-Land Mayhem! | Nintendo Software Technology | Nintendo | November 14, 2010 (NA) |
| Mario vs. Donkey Kong 2: March of the Minis | Nintendo | Nintendo | September 25, 2006 (NA) |
| Marker Man Adventures | Glyphic Entertainment | Majesco Entertainment | November 11, 2008 (NA) |
| Marvel Nemesis: Rise of the Imperfects | EA Canada, Sensory Sweep Studios | EA Games | October 11, 2005 (NA) |
| Marvel Super Hero Squad | Halfbrick | THQ | October 20, 2009 (NA) |
| Marvel Super Hero Squad: The Infinity Gauntlet | THQ | THQ | November 16, 2010 (NA) |
| Marvel Trading Card Game | 1st Playable Productions | Konami | May 22, 2007 (NA) |
| Marvel: Ultimate Alliance 2 | Vicarious Visions | Activision | September 15, 2009 (NA) |
| Mary King's Riding School | Coyote Console | Ghostlight, Midas Interactive Entertainment | August 29, 2008 (PAL) |
| Master of Illusion | 8ing, Tenyo | Nintendo | November 16, 2006 (JP) |
| Master of the Monster Lair | Global A Entertainment | Atlus, Global A Entertainment, Rising Star Games | October 25, 2007 (JP) |
| Matchstick Puzzle by DS | Ertain | Ertain, DreamCatcher Games | February 11, 2008 (PAL) |
| Math Blaster in the Prime Adventure | Knowledge Adventure | Knowledge Adventure | February 3, 2008 (NA) |
| Math Play | Denyu-Sha | Denyu-Sha, Natsume, Ubisoft | September 7, 2006 (JP) |
| Mawashite Tsunageru Touch Panic | Aki Corporation | Nintendo | May 25, 2006 (JP) |
| Mazes of Fate DS | Sabarasa | Graffiti Entertainment | September 9, 2008 (NA) |
| Metcha! Taiko no Tatsujin DS: Nanatsu no Shima no Daibouken | Namco Bandai Games | Namco Bandai Games | April 24, 2008 (JP) |
| Mechanic Master | Midway Games | Midway Games | October 24, 2008 (PAL) |
| MechAssault: Phantom War | Backbone Entertainment | Eidos Interactive, Majesco Entertainment | September 12, 2006 (NA) |
| Medarot DS | Delta Arts | Rocket Company | May 27, 2010 (JP) |
| Mega Brain Boost | Interchannel | Majesco Entertainment | January 22, 2008 (NA) |
| Mega Man Battle Network 5: Double Team DS | Capcom | Capcom, Nintendo | July 21, 2005 (JP) |
| Mega Man Star Force 2: Zerker × Ninja | Capcom | Capcom | November 22, 2007 (JP) |
| Mega Man Star Force 2: Zerker × Saurian | Capcom | Capcom | November 22, 2007 (JP) |
| Mega Man Star Force 3: Black Ace | Capcom | Capcom | November 13, 2008 (JP) |
| Mega Man Star Force 3: Red Joker | Capcom | Capcom | November 13, 2008 (JP) |
| Mega Man Star Force: Dragon | Capcom | Capcom | December 14, 2006 (JP) |
| Mega Man Star Force: Leo | Capcom | Capcom | December 14, 2006 (JP) |
| Mega Man Star Force: Pegasus | Capcom | Capcom | December 14, 2006 (JP) |
| Mega Man Zero Collection | Inti Creates | Capcom | June 8, 2010 (NA) |
| Mega Man ZX | Inti Creates | Capcom | July 6, 2006 (JP) |
| Mega Man ZX Advent | Inti Creates | Capcom | July 12, 2007 (JP) |
| Meitantei Conan & Kindaichi Shounen no Jikenbou | Namco Bandai Games | Namco Bandai Games | February 5, 2009 (JP) |
| Metal Fight Beyblade DS | Amber | Hudson Soft | March 26, 2009 (JP) |
| Metal Max 3 | Enterbrain | Kadokawa Games | July 29, 2010 (JP) |
| Metal Saga: Hagane no Kisetsu | Crea-Tech | Success Corporation | June 15, 2006 (JP) |
| Metal Slug 7 | SNK Playmore | SNK Playmore, Ignition Entertainment | July 17, 2008 (JP) |
| Meteos | Q Entertainment, Sora Ltd. | Bandai, Nintendo | March 10, 2005 (JP) |
| Meteos: Disney Magic | Q Entertainment, Aspect Co., Ltd., Platinum Egg | Buena Vista Games | February 20, 2007 (NA) |
| Metroid Prime Hunters | Nintendo Software Technology, Retro Studios | Nintendo | March 20, 2006 (NA) |
| Metroid Prime Pinball | Fuse Games | Nintendo | October 24, 2005 (NA) |
| Miami Law | Hudson Soft | Hudson Soft | June 9, 2009 (NA) |
| Miami Nights: Singles in the City | Gameloft | Ubisoft | January 15, 2008 (NA) |
| Michael Jackson: The Experience | Ubisoft | Ubisoft | November 23, 2010 (NA) |
| Micro Machines V4 | Supersonic Software | Codemasters | January 5, 2007 (PAL) |
| Midnight Play! Pack | Gameloft | Ubisoft | June 6, 2008 (PAL) |
| Might & Magic: Clash of Heroes | Capybara Games | Ubisoft | December 1, 2009 (NA) |
| Mind Quiz: Your Brain Coach | Ubisoft | Sega, Ubisoft | September 14, 2006 (JP) |
| MinDStorm | ASK | 505 Games, ASK, Valcon Games | September 1, 2006 (JP) |
| MinDStorm 2 | ASK | 505 Games, ASK | February 19, 2009 (JP) |
| Mini Ninjas | IO Interactive | Eidos Interactive | September 8, 2009 (NA) |
| Mini RC Rally | Summitsoft Entertainment | Summitsoft Entertainment | December 12, 2006 (NA) |
| Minna no DS Curling | November 22, 2006 (JP) | ||
| Mirakuru! Mimika DS | Culture Brain | Culture Brain | January 22, 2009 (JP) |
| Miss Spider's Sunny Patch Friends: Harvest Time Hop and Fly | Shin'en Multimedia | The Game Factory | May 30, 2006 (NA) |
| Mister Slime | Lexis Numerique | SouthPeak Games, DTP Entertainment | July 17, 2008 (NA) |
| Mobile Suit Gundam 00 | Namco Bandai Games | Namco Bandai Games | March 27, 2008 (JP) |
| Moero! Nekketsu Rhythm Damashii Osu! Tatakae! Ouendan 2 | iNiS | Nintendo | May 17, 2007 (JP) |
| MLB Power Pros 2008 | Konami | 2K Sports | August 25, 2008 (NA) |
| Moetan DS | Idea Factory | Idea Factory | July 24, 2008 (JP) |
| Monopoly / Boggle / Yahtzee / Battleship | Sensory Sweep Studios | Atari | December 13, 2005 (NA) |
| Monster Bomber | Taito Corporation | Red Ant Enterprises, Taito Corporation | March 23, 2006 (JP) |
| Monster Farm DS 2: Yomigaeru! Master Breeder Densetsu | Tecmo | Tecmo | August 7, 2008 (JP) |
| Monster Frenzy | November 11, 2008 (PAL) | ||
| Monster High: 13 Wishes | Torus Games | Little Orbit | October 29, 2013 (NA) |
| Monster High: Ghoul Spirit | THQ | THQ | October 25, 2011 (NA) |
| Monster High: Skultimate Roller Maze | Game Machine Studios | Little Orbit | November 13, 2012 (NA) |
| Monster House | Artificial Mind and Movement | THQ | July 18, 2006 (NA) |
| Monster Jam | Torus Games | Activision | November 13, 2007 (NA) |
| Monster Jam: Urban Assault | Torus Games | Activision | October 28, 2008 (NA) |
| Monster Lab | Backbone Entertainment | Eidos Interactive | October 31, 2008 (PAL) |
| Monster Racers | Koei | Koei | January 22, 2009 (JP) |
| Monster Tale | DreamRift | Majesco Entertainment | March 16, 2011 (NA) |
| Monster Trucks DS | Skyworks Technologies | Majesco Entertainment, THQ | December 11, 2005 (NA) |
| Monsters vs. Aliens | Activision | Activision | March 24, 2009 (NA) |
| Moon | Renegade Kid | Gamebridge, Mastiff | January 13, 2009 (NA) |
| Moshi Monsters: Katsuma Unleashed | Black Lantern Studios | Activision | October 11, 2013 (EU) |
| Moshi Monsters: Moshling Zoo | Mind Candy | Activision | November 6, 2011 (NA) |
| Moshi Monsters: Moshlings Theme Park | Black Lantern Studios | Activision | October 26, 2012 (EU) |
| Moto Racer DS | Artefacts | Nobilis | November 28, 2008 (EU) |
| Mr. Bean | Blast! Entertainment | Blast! Entertainment | March 14, 2008 (PAL) |
| Mr. Driller Drill Spirits | Namco | Namco, Nintendo | November 30, 2004 (NA) |
| MTV Fan Attack | Le Caillou | Mindscape | November 22, 2007 (PAL) |
| The Mummy: Tomb of the Dragon Emperor | Artificial Mind and Movement | Sierra Entertainment | July 22, 2008 (NA) |
| The Mushitori Oukoku | D3 Publisher | 505 Game Street, D3 Publisher | June 30, 2005 (JP) |
| Mushroom Men: Rise of the Fungi | Red Fly Studio | Gamecock Media Group | October 11, 2008 (PAL) |
| MX vs. ATV: Untamed | Rainbow Studios | THQ | December 17, 2007 (NA) |
| My Animal Centre in Africa | Europress | 505 Game Street, Europress | November 23, 2007 (PAL) |
| My Animal Centre in Australia | Deep Silver | Deep Silver | November 23, 2007 (EU) |
| My Baby 3 & Friends | Nobilis | Majesco Entertainment | October 12, 2010 (NA) |
| My Baby Boy | Nobilis | Nobilis, SouthPeak Games | October 28, 2008 (NA) |
| My Baby First Steps | Nobilis | Nobilis, SouthPeak Games | November 11, 2009 (NA) |
| My Baby Girl | Nobilis | Nobilis, SouthPeak Games | November 4, 2008 (NA) |
| My Chinese Coach | Ubisoft | Ubisoft | August 26, 2008 (NA) |
| My Dress-Up | Oxygen Games | Oxygen Games | October 11, 2008 (PAL) |
| My English Coach | Ubisoft | Ubisoft | March 10, 2009 (NA) |
| My Fashion Studio | 505 Games | Ubisoft | June 10, 2008 (NA) |
| My French Coach | Ubisoft | Ubisoft | November 6, 2007 (NA) |
| My French Coach Level 2: Intermediate | Ubisoft | Ubisoft | November 23, 2007 (PAL) |
| My Frogger Toy Trials | Konami | Konami | November 13, 2006 (NA) |
| My Fun Facts Coach | Ubisoft | Ubisoft | December 2, 2008 (NA) |
| My Healthy Cooking Coach | Ubisoft | Ubisoft | June 23, 2009 (NA) |
| My Horse and Me | W!Games | Atari | November 23, 2007 (PAL) |
| My Japanese Coach | Ubisoft | Ubisoft | September 23, 2008 (NA) |
| My Little Baby | dtp Young Entertainment | cdv Software Entertainment | September 11, 2008 (NA) |
| My Little Flufties | DK Games | Lexicon Entertainment | July 13, 2007 (PAL) |
| My Make-Up | Oxygen Games | Oxygen Games | October 21, 2008 (PAL) |
| My Pet Dolphin | Starfish SD | Starfish SD, 505 Games | September 13, 2007 (JP) |
| My Pet Dolphin 2 | Starfish SD | Starfish SD, 505 Games | September 18, 2008 (JP) |
| My Pet Hotel 2 | DTP Entertainment | DTP Entertainment, Eidos Interactive | September 26, 2008 (PAL) |
| My Pet Shop | Taito Corporation | Square Enix | February 27, 2009 (PAL) |
| My Riding Stables | DTP Entertainment | Eidos Interactive | April 24, 2008 (PAL) |
| My SAT Coach | Ubisoft Montreal | Ubisoft | September 23, 2008 (NA) |
| My Secret Diary | Oxygen Games | Oxygen Games | October 17, 2008 (PAL) |
| My Secret World by Imagine | Ubisoft | Ubisoft | September 16, 2008 (NA) |
| My Spanish Coach | Ubisoft | Ubisoft | November 6, 2007 (NA) |
| My Spanish Coach Level 2: Intermediate | Ubisoft | Ubisoft | November 23, 2007 (PAL) |
| My Stop Smoking Coach: Allen Carr's EasyWay | Ubisoft | Ubisoft | November 11, 2008 (NA) |
| My Weight Loss Coach | Ubisoft Montreal | Ubisoft | June 20, 2008 (PAL) |
| My Word Coach | Ubisoft Montreal | Ubisoft | November 6, 2007 (NA) |
| My World, My Way | Global A Entertainment | Atlus, Global A Entertainment, Rising Star Games | June 12, 2008 (JP) |
| MySims | EA Redwood Shores | EA Games, Electronic Arts | September 18, 2007 (NA) |
| MySims Agents | EA Redwood Shores | Electronic Arts | September 25, 2009 (NA) |
| MySims Kingdom | EA Redwood Shores | Electronic Arts | October 28, 2008 (NA) |
| MySims Party | EA Montreal | Electronic Arts | March 10, 2009 (NA) |
| MySims Racing | EA Black Box | Electronic Arts | June 8, 2009 (NA) |
| Myst | Cyan Worlds | Midway Games, Empire Interactive | December 7, 2007 (PAL) |
| Mystery Case Files: MillionHeir | Big Fish Games | Nintendo | September 8, 2008 (NA) |
| Mystery Dungeon: Shiren the Wanderer | Chunsoft | Sega | March 4, 2008 (NA) |
| Mystery Mansion | Dreams Interactive | 505 Games | May 1, 2008 (PAL) |
| Mystery P.I.: Portrait of a Thief | Black Lantern Studios | PopCap Games | December 19, 2008 (PAL) |
| N+ | SilverBirch Studios, Slick Entertainment | Atari | August 26, 2008 (NA) |
| Nacho Libre | Budcat Creations | Eidos Interactive, Majesco Entertainment | October 26, 2006 (NA) |
| Nakayoshi Quiz no Oshigo to Theme Park | Culture Brain | Culture Brain | June 16, 2011 (JP) |
| The Naked Brothers Band The Video Game | Barking Lizards Technology | THQ | October 20, 2008 (NA) |
| Namco Museum DS | Namco, Namco Bandai Games | Namco Bandai Games, Atari | September 18, 2007 (NA) |
| Nanashi no Game | Square Enix | Square Enix | July 3, 2008 (JP) |
| Nanashi no Game Me | Square Enix | Square Enix | August 27, 2009 (JP) |
| Nancy Drew: Deadly Secret of Olde World Park | Gorilla Systems | Eidos Interactive, Majesco Entertainment | September 18, 2007 (NA) |
| Nancy Drew: The Hidden Staircase | Gorilla Systems | Majesco Entertainment | September 18, 2007 (NA) |
| Nancy Drew: The Mystery of the Clue Bender Society | Gorilla Systems | Majesco Entertainment | July 23, 2008 (NA) |
| Nankoku Sodachi DS | Commseed | Commseed | December 24, 2009 (JP) |
| Nanostray | Shin'en Multimedia | Majesco Entertainment, Taito Corporation | July 19, 2005 (PAL) |
| Nanostray 2 | Shin'en Multimedia | Codemasters, Majesco Entertainment | March 11, 2008 (NA) |
| Napoleon Dynamite: The Game | 7 Studios | Crave Entertainment | October 30, 2007 (NA) |
| Naruto: Ninja Council 2 European Version | Takara Tomy | Takara Tomy, Tomy | April 21, 2005 (JP) |
| Naruto: Ninja Council 3 | Aspect | D3 Publisher, Tomy, Nintendo | April 27, 2006 (JP) |
| Naruto: Ninja Destiny | Takara Tomy | D3 Publisher, Namco Bandai Games, Tomy | December 14, 2006 (JP) |
| Naruto: Path of the Ninja | Tose | D3 Publisher | October 23, 2007 (NA) |
| Naruto: Path of the Ninja 2 | Tose | D3 Publisher | July 13, 2006 (JP) |
| Naruto RPG 2: Chidori vs. Rasengan | Tomy | Tomy | July 14, 2005 (JP) |
| Naruto RPG 3: Reijuu vs. Konoha Shoutai | Tomy | Tomy | July 13, 2006 (JP) |
| Naruto Shippūden: Dairansen! Kage Bunshin Emaki | Takara Tomy | Takara Tomy | February 14, 2008 (JP) |
| Naruto Shippūden: Naruto vs. Sasuke | Takara Tomy | Takara Tomy, Tomy | July 10, 2008 (JP) |
| Naruto Shippūden: Ninja Council 4 | Takara Tomy | Takara Tomy, Tomy | April 27, 2006 (JP) |
| Naruto Shippūden: Ninja Destiny 2 | Takara Tomy | Takara Tomy, Tomy | April 24, 2008 (JP) |
| Naruto Shippūden: Ninja Destiny 3 | Takara Tomy | Takara Tomy | April 29, 2009 (JP) |
| Naruto Shippūden: Path of the Ninja | October 23, 2007 (NA) | ||
| Naruto Shippūden: Path of the Ninja 2 | July 13, 2006 (JP) | ||
| Naruto Shippūden: Saikyou Ninja Daikesshu 3 | April 21, 2005 (JP) | ||
| Naruto Shippūden: Shinobi Rumble | Takara Tomy | Takara Tomy | April 22, 2010 (JP) |
| National Geographic Panda | Namco Bandai Games | Namco Bandai Games America | November 11, 2008 (NA) |
| Need for Speed Carbon: Own the City | Exient Entertainment | EA Games | October 31, 2006 (NA) |
| Need for Speed: Most Wanted | EA Canada | Electronic Arts | November 11, 2005 (EU) |
| Need for Speed: Nitro | Firebrand Games | EA Games | November 2, 2009 (NA) |
| Need for Speed: ProStreet | Exient Entertainment | EA Games | November 13, 2007 (NA) |
| Need for Speed: Undercover | Firebrand Games | Electronic Arts | November 17, 2008 (NA) |
| Need for Speed: Underground 2 | EA Canada | EA Games | May 10, 2005 (NA) |
| Negima | March 20, 2007 (JP) | ||
| Neighbours from Hell | JoWooD Productions | Pinnacle | November 21, 2008 (PAL) |
| Neopets Puzzle Adventure | Griptonite Games, Infinitive Interactive | Capcom | November 25, 2008 (NA) |
| Nep League DS | Jaleco Entertainment | Jaleco Entertainment | December 6, 2007 (JP) |
| Nervous Brickdown | Arkedo Studio | Eidos Interactive, Success | June 26, 2007 (NA) |
| Neves | Yuke's | Atlus, Ignition Entertainment, Yuke's | November 6, 2007 (NA) |
| The New Adventures of Moomin: The Great Autumn Party | Yuke's | Atlus, Gaffiti Entertainment, Yuke's | March 13, 2009 (NA) |
| The New Adventures of Moomin: The Mysterious Howling | Yuke's | Atlus, Gaffiti Entertainment, Yuke's | April 30, 2008 (EU) |
| New Carnival Games | Cat Daddy Games | 2K Play | September 21, 2010 (NA) |
| New International Track & Field | Konami | Konami | July 22, 2008 (NA) |
| New Super Mario Bros. | Nintendo | Nintendo | May 15, 2006 (NA) |
| New Unō Kids DS | IE Institute | IE Institute | November 13, 2008 (JP) |
| The New York Times Crosswords | Budcat Creations | Majesco | May 29, 2007 (NA) |
| New Zealand Story Revolution | Marvelous Entertainment | CyberFront, Ignition Entertainment, Rising Star Games | February 2, 2007 (PAL) |
| Nicktoons: Attack of the Toybots | THQ | THQ | October 23, 2007 (NA) |
| Nicktoons: Battle for Volcano Island | Natsume | THQ | October 24, 2006 (NA) |
| Nicktoons MLB | Black Lantern Studios | 2K Play | September 13, 2011 (NA) |
| Nicktoons Unite! | THQ | THQ | March 3, 2006 (PAL) |
| Night at the Museum: Battle of the Smithsonian | Majesco Entertainment | Majesco Entertainment | May 5, 2009 (NA) |
| Nine Hours, Nine Persons, Nine Doors | Chunsoft | Spike, Aksys Games | December 10, 2009 (JP) |
| Ninja Gaiden Dragon Sword | Team Ninja | Tecmo, Ubisoft | March 20, 2008 (JP) |
| Ninja Reflex | Sanzaru Games | Electronic Arts | March 4, 2008 (NA) |
| Ninjatown | Venan Entertainment | SouthPeak Games | October 28, 2008 (NA) |
| Nintendo DS Browser | Nintendo, Opera Software | Nintendo | July 24, 2006 (JP) |
| Nintendo MP3 Player | Nintendo | Nintendo | September 14, 2005 (JP) |
| Nintendogs: Best Friends | Nintendo | Nintendo | October 24, 2005 (NA) |
| Nintendogs: Chihuahua and Friends | Nintendo | Nintendo | April 21, 2005 (JP) |
| Nintendogs: Dachshund and Friends | Nintendo | Nintendo | April 21, 2005 (JP) |
| Nintendogs: Dalmatian and Friends | Nintendo | Nintendo | June 16, 2006 (PAL) |
| Nintendogs: Lab and Friends | Nintendo | Nintendo | April 21, 2005 (JP) |
| Nobunaga no Yabou DS 2 | Koei | Koei | July 31, 2008 (JP) |
| Nobunaga's Ambition DS | Koei | Koei | April 27, 2006 (JP) |
| Nodame Cantabile | Namco Bandai Games | Namco Bandai Games | April 19, 2007 (JP) |
| Nora to Toki no Kōbō: Kiri no Mori no Majo | Atlus | Atlus | July 21, 2011 (JP) |
| Nostalgia | Matrix Software, Red Entertainment | Ignition Entertainment, Tecmo | November 6, 2008 (JP) |
| NRL Mascot Mania | Wicked Witch Software | Tru Blu Games | June 26, 2009 (AU) |
| O.M.G. 26: Our Mini Games | Tommo | Tommo | October 30, 2007 (NA) |
| Ochaken no Daibouken: Honwaku Yumemiru Sekai Ryoukou | MTO | MTO | December 20, 2007 (JP) |
| Ochaken no Daibouken 2: Yume Ippai no Omocha Hako | MTO | MTO | December 18, 2008 (JP) |
| Ochaken no Heya DS | MTO | MTO | April 27, 2006 (JP) |
| Ochaken no Heya DS 2 | MTO | MTO | January 18, 2007 (JP) |
| Ochaken no Heya DS 3 | MTO | MTO | May 22, 2008 (JP) |
| Ochaken no Heya DS 4 | MTO | MTO | November 26, 2009 (JP) |
| Oekaki Puzzle Battle Vol. 1: Yuusha-Oh GaoGaiGar Version | Sunrise Interactive | Sunrise Interactive | December 8, 2005 (JP) |
| Oha Star 645: Musshees no Fushigi na Nouen - Yoshimoto Geinin to Tomodachi Net | Culture Brain | Culture Brain | November 23, 2011 (JP) |
| Okaeri! Chibi-Robo! Happy Richie Oosouji! | Skip Ltd. | Nintendo | January 23, 2009 (JP) |
| Ōkamiden | Capcom | Capcom | September 30, 2010 (JP) |
| One Piece: Gear Spirit | Matrix Software | Namco Bandai Games | August 30, 2007 (JP) |
| One Piece: Gigant Battle! | Ganbarion | Bandai Namco Games | September 9, 2010 (JP) |
| One Piece: Gigant Battle! 2 - New World | Ganbarion | Bandai Namco Games | November 17, 2011 (JP) |
| Onegai My Melody | TDK Core | TDK Core | December 22, 2005 (JP) |
| Ontamarama | Noise Factory | Atlus, Noise Factory | June 7, 2007 (JP) |
| Open Season | Ubisoft | Ubisoft | September 19, 2006 (NA) |
| Operation: Vietnam | Coyote Console | Eidos Interactive, Majesco Entertainment | August 20, 2007 (NA) |
| Orcs & Elves | Fountainhead Entertainment, id Software | Electronic Arts | November 13, 2007 (NA) |
| Original Frisbee Disc Sports: Ultimate & Golf | Skyworks Technologies | Destination Software | September 24, 2007 (NA) |
| Oshare Majo: Love and Berry | Sega | Sega | November 22, 2006 (JP) |
| Oshare Princess DS: Oshare ni Koishite! | Culture Brain | Culture Brain | December 16, 2006 (JP) |
| Oshare Princess DS: Oshare ni Koi Shite 2 | Culture Brain | Culture Brain | April 24, 2008 (JP) |
| Osu! Tatakae! Ouendan | iNiS | Nintendo | July 28, 2005 (JP) |
| Otona no Onnaryoku Kentei | Konami | Konami | June 28, 2007 (JP) |
| Our House | Budcat Creations | Majesco Entertainment | November 11, 2008 (NA) |
| Over the Hedge | Vicarious Visions | Activision | May 5, 2006 (NA) |
| Over the Hedge: Hammy Goes Nuts! | Amaze Entertainment | Activision | October 24, 2006 (NA) |
| Overlord: Minions | Climax Studios | Codemasters | June 23, 2009 (NA) |
| Pac 'n Roll | Namco | Namco, Nintendo | July 28, 2005 (JP) |
| Pac-Man World 3 | Blitz Games | Namco | December 7, 2005 (NA) |
| Pac-Pix | Namco | Namco | March 10, 2005 (JP) |
| Paint By DS | Ertain | Mercury Games | August 31, 2006 (JP) |
| Pang: Magical Michael | Mitchell Corporation | Rising Star Games | September 17, 2010 (EU) |
| Panzer Tactics DS | Sproing Interactive Media | 10tacle Studios, Conspiracy Entertainment, QV Software | November 6, 2007 (NA) |
| The Party Game | D3 Publisher | D3 Publisher | November 23, 2005 (JP) |
| The Party Unou Quiz | D3 Publisher | D3 Publisher | December 7, 2006 (JP) |
| Pass the Pigs | THQ | THQ | October 20, 2008 (PAL) |
| Paul Sloane & Des MacHale's Intriguing Tales | Level-5 | Level-5 | May 21, 2009 (JP) |
| Paul Sloane & Des MacHale's Intriguing Tales 2 | Level-5 | Level-5 | September 3, 2009 (JP) |
| Pawly Pets: My Animal Centre in Africa | December 11, 2006 (PAL) | ||
| Pawly Pets: My Pet Hotel | Ubisoft | Ubisoft | August 29, 2008 (PAL) |
| Pawly Pets: My Vet Practice | DTP Entertainment | ValuSoft, Ubisoft | February 2, 2007 (PAL) |
| Paws and Claws Pet Resort | THQ | THQ | February 4, 2008 (NA) |
| Paws and Claws: Pet Vet | Radon Labs | ValuSoft | January 3, 2007 (NA) |
| Paws and Claws: Pet Vet 2 | ValuSoft | THQ | August 7, 2007 (NA) |
| Paws and Claws: Best Friends - Dogs & Cats | Sproing Interactive Media | Eidos InteractivePAL, THQNA | September 14, 2007 (PAL) |
| PDC World Championship Darts 2009 | Rebellion Developments | Oxygen Games | May 29, 2009 (EU) |
| Peggle: Dual Shot | Q Entertainment | PopCap Games | February 25, 2009 (NA) |
| Pen 1 Grand Prix: Penguin no Mondai Special | Konami | Konami | December 10, 2009 (JP) |
| Peppa Pig | Asylum Entertainment | Pinnacle | November 28, 2008 (EU) |
| Percy Jackson & the Olympians: The Lightning Thief | Griptonite Games | Activision | February 11, 2010 (NA) |
| Personal Trainer: Cooking | Nintendo | Nintendo | July 20, 2006 (NA) |
| Personal Trainer: Math | Jupiter | Shogakukan, Nintendo | January 13, 2007 (JP) |
| Personal Trainer: Walking | Creatures Inc. | Nintendo | November 1, 2008 (JP) |
| Pet Adoption Center | Ubisoft | Ubisoft | June 30, 2008 (NA) |
| Pet Alien: An Intergalactic Puzzlepalooza | Shin'en Multimedia | The Game Factory | August 28, 2007 (NA) |
| Pet Pals: Animal Doctor | Legacy Interactive | Majesco Entertainment | February 7, 2008 (NA) |
| Peter Jackson's King Kong: The Official Game of the Movie | Ubisoft Casablanca | Ubisoft | November 21, 2005 (NA) |
| Petz: Bunnyz | Ubisoft | Digital Kids, Ubisoft | March 4, 2008 (NA) |
| Petz: Catz 2 | Ubisoft | Ubisoft | November 9, 2007 (PAL) |
| Petz: Dogz 2 | Ubisoft | Ubisoft | October 12, 2007 (PAL) |
| Petz: Dogz Fashion | Ubisoft | Ubisoft | June 17, 2008 (NA) |
| Petz: Dogz Pack | Ubisoft | Ubisoft | November 11, 2008 (NA) |
| Petz: Hamsterz 2 | Ubisoft | Ubisoft | November 9, 2007 (PAL) |
| Petz: Hamsterz Life 2 | Ubisoft | Ubisoft | November 13, 2007 (NA) |
| Petz Rescue: Endangered Paradise | Phoenix Interactive Entertainment | Ubisoft | November 11, 2008 (NA) |
| Petz Rescue: Ocean Patrol | Magic Pockets | Ubisoft | October 11, 2008 (NA) |
| Petz Rescue: Wildlife Vet | Lexis Numerique, Virtual Toys | Ubisoft | October 11, 2008 (NA) |
| Petz Wild Animals: Dolphinz | October 16, 2007 (NA) | ||
| Phantasy Star Zero | Sega | Sega | December 25, 2008 (JP) |
| Phineas and Ferb | Altron | Disney Interactive Studios | February 3, 2009 (NA) |
| Phoenix Wright: Ace Attorney | Capcom | Capcom | September 15, 2005 (JP) |
| Phoenix Wright: Ace Attorney: Justice for All | Capcom | Capcom | October 26, 2006 (JP) |
| Phoenix Wright: Ace Attorney: Trials and Tribulations | Capcom | Capcom | August 23, 2007 (JP) |
| Pic Pic | Success Corporation | 505 Games, Success Corporation | April 26, 2007 (JP) |
| Picross 3D | Nintendo | Nintendo | March 12, 2009 (JP) |
| Picross DS | Jupiter | Nintendo | January 25, 2007 (JP) |
| PictoImage | Sega | Sega | September 27, 2007 (JP) |
| Pinchcliffe Grand Prix | Caprino Video Game | Ravn Studio | April 23, 2010 (EU) |
| Ping Pals | WayForward Technologies | THQ | December 8, 2004 (NA) |
| Pinky Street Kira Kira * Music Night | December 20, 2007 (JP) | ||
| Pinky Street: Kira Kira * Music Hour | October 26, 2006 (JP) | ||
| Pipe Mania | Empire Interactive | Atari, Empire Interactive | September 23, 2008 (NA) |
| Pippa Funnell | Ubisoft | Ubisoft | October 27, 2006 (PAL) |
| Pippa Funnell 2: Farm Adventures | Ubisoft | Ubisoft | October 12, 2007 (PAL) |
| Pirates of the Caribbean: At World's End | Amaze Entertainment | Disney Interactive Studios, Eurocom | May 22, 2007 (NA) |
| Pirates of the Caribbean: Dead Man's Chest | Griptonite Games | Buena Vista Games, D3 Publisher | June 27, 2006 (NA) |
| Pirates: Duels on the High Seas | Oxygen Games | Oxygen Games | September 12, 2008 (PAL) |
| Planet 51 | Pyro Studios | Sega | November 17, 2009 (NA) |
| Planet Puzzle League | Intelligent Systems | Nintendo | April 26, 2007 (JP) |
| Plants vs. Zombies | PopCap Games | PopCap Games | January 18, 2011 (NA) |
| Platinum Sudoku | Gameloft | Ubisoft | May 11, 2007 (PAL) |
| Plushees | Destineer | Destineer | April 11, 2008 (NA) |
| Pocket Pets | Agatsuma Entertainment | Agatsuma Entertainment, O3 Entertainment | April 26, 2007 (JP) |
| Pogo Island | EA Games | EA Games | March 26, 2007 (NA) |
| Point Blank DS | Namco Bandai Games | Namco | May 18, 2006 (JP) |
| Pokémon Black | Game Freak | Nintendo | September 18, 2010 (JP) |
| Pokémon Black 2 | Game Freak | Nintendo | June 23, 2012 (JP) |
| Pokémon Conquest | Tecmo Koei | Nintendo | March 17, 2012 (JP) |
| Pokémon Dash | Ambrella | Nintendo | December 2, 2004 (JP) |
| Pokémon Diamond | Game Freak | Nintendo | September 28, 2006 (JP) |
| Pokémon HeartGold | Game Freak | Nintendo | September 12, 2009 (JP) |
| Pokémon Mystery Dungeon: Blue Rescue Team | ChunSoft | Nintendo | November 17, 2005 (JP) |
| Pokémon Mystery Dungeon: Explorers of Darkness | ChunSoft | Nintendo | September 13, 2007 (JP) |
| Pokémon Mystery Dungeon: Explorers of Sky | ChunSoft | Nintendo | April 18, 2009 (JP) |
| Pokémon Mystery Dungeon: Explorers of Time | ChunSoft | Nintendo | September 13, 2007 (JP) |
| Pokémon Pearl | Game Freak | Nintendo | September 28, 2006 (JP) |
| Pokémon Platinum | Game Freak | Nintendo | September 13, 2008 (JP) |
| Pokémon Ranger | HAL Laboratory | Nintendo | March 23, 2006 (JP) |
| Pokémon Ranger: Guardian Signs | Creatures Inc. | Nintendo | March 6, 2010 (JP) |
| Pokémon Ranger: Shadows of Almia | HAL Laboratory | Nintendo | March 20, 2008 (JP) |
| Pokémon SoulSilver | Game Freak | Nintendo | September 12, 2009 (JP) |
| Pokémon Trozei! | Genius Sonority | Nintendo | October 20, 2005 (JP) |
| Pokémon White | Game Freak | Nintendo | September 18, 2010 (JP) |
| Pokémon White 2 | Game Freak | Nintendo | June 23, 2012 (JP) |
| Polarium | Mitchell Corporation | Nintendo | December 2, 2004 (JP) |
| Pony Friends | Eidos Interactive | Eidos Interactive, Starfish SD | May 18, 2007 (PAL) |
| Pony Friends: Mini Breeds Edition | Eidos Interactive | Eidos Interactive | November 3, 2008 (NA) |
| Pony LUV | Activision | Activision | October 2, 2006 (NA) |
| Pop Cutie! Street Fashion Simulation | Koei | Koei | April 24, 2008 (JP) |
| Pop Town | HuneX | 505 Games, Dimple Entertainment | December 20, 2007 (JP) |
| Poptropica Adventures | Ubisoft | Ubisoft | November 6, 2012 (NA) |
| Populous DS | Electronic Arts | Electronic Arts, Rising Star Games, Xseed Games | February 21, 2008 (JP) |
| Postman Pat | Blast! Entertainment | Blast! Entertainment | March 14, 2008 (JP) |
| Postman Pat Special Delivery Service | Uacari | Avanquest | July 17, 2009 (EU) |
| Poupée Girl DS | Alvion | Alvion | December 17, 2009 (JP) |
| Poupée Girl DS 2: Sweet Pink Style | Alvion | Alvion | December 10, 2010 (JP) |
| Poupée Girl DS 2: Elegant Mint Style | Alvion | Alvion | December 10, 2010 (JP) |
| Power Play Pool | System 3 | Conspiracy Entertainment, System 3 | October 26, 2007 (NA) |
| Power Play Tennis | Codemasters | Codemasters | February 11, 2008 (NA) |
| Power Pocket Koushien | Konami | Konami | August 4, 2005 (JP) |
| Power Pro Kun Pocket 8 | Konami | Konami | December 1, 2005 (JP) |
| Power Pro Kun Pocket 9 | Konami | Konami | December 7, 2006 (JP) |
| Power Pro Kun Pocket 10 | Konami | Konami | December 6, 2007 (JP) |
| Power Pro Kun Pocket 11 | Konami | Konami | December 4, 2008 (JP) |
| Power Pro Kun Pocket 12 | Konami | Konami | December 3, 2009 (JP) |
| Power Pro Kun Pocket 13 | Konami | Konami | November 25, 2010 (JP) |
| Power Rangers Samurai | Namco Bandai Games | Namco Bandai Games | November 22, 2011 (NA) |
| Power Rangers: Super Legends | Handheld Games | Disney Interactive Studios | October 23, 2007 (NA) |
| Powerbike | Tornado Studios | Majesco Entertainment | November 11, 2008 (PAL) |
| Powerful Golf | Konami | Konami | March 17, 2011 (JP) |
| Powershot Pinball Constructor | Involgamus | Oxygen Games | March 26, 2008 (PAL) |
| Press Your Luck | Ubisoft | Ubisoft | October 27, 2009 (NA) |
| Prey the Stars | Koei | Koei | September 25, 2008 (JP) |
| The Price Is Right 2010 | Ubisoft | Ubisoft | September 22, 2009 (NA) |
| The Price Is Right | Ubisoft | Ubisoft | September 9, 2008 (NA) |
| Prince of Persia: The Fallen King | Ubisoft | Ubisoft | December 2, 2008 (NA) |
| The Princess and the Frog | Griptonite Games | Disney Interactive Studios | November 17, 2009 (NA) |
| Princess Debut | Cave | Cave, Natsume | May 29, 2008 (JP) |
| Princess Maker 4 Special Edition | CyberFront | CyberFront | September 25, 2008 (JP) |
| Princess Natasha | Frame Studios Interactive | Destination Software | October 3, 2006 (NA,PAL) |
| Princess on Ice | Arc System Works | 505 Games, Aksys Games, Arc System Works | April 25, 2008 (PAL) |
| Prism: Light the Way | Eidos Interactive | Eidos Interactive, Interchannel | October 17, 2007 (NA) |
| Pro Evolution Soccer 2008 | Konami | Konami | October 25, 2007 (JP) |
| Pro Evolution Soccer 6 | Konami | Konami | November 2, 2006 (JP) |
| Professional Fisherman's Tour: Northern Hemisphere | UFO Interactive Games | 505 Game Street, Starfish SD, Tommo | August 29, 2007 (NA) |
| Professor Brainium's Games | Bold Games | Frontline Studios | March 31, 2008 (NA) |
| Professor Heinz Wolff's Gravity | Deep Silver | Deep Silver | November 11, 2008 (NA) |
| Professor Layton and the Curious Village | Level-5 | Level-5, Nintendo | February 15, 2007 (JP) |
| Professor Layton and the Diabolical Box | Level-5 | Level-5, Nintendo | November 29, 2007 (JP) |
| Professor Layton and the Last Specter | Level-5 | Level-5, Nintendo | November 26, 2009 (JP) |
| Professor Layton and the Unwound Future | Level-5 | Level-5, Nintendo | November 27, 2008 (JP) |
| Project Hacker | Red Entertainment | Nintendo | July 13, 2006 (JP) |
| Pucca Power Up | Rising Star Games | UFO Interactive Games | December 9, 2010 (KOR) |
| Puchi Eva: Evangelion @ Game | Bandai | Namco Bandai Games | March 20, 2008 (JP) |
| Puchi Puchi Virus | Jaleco Entertainment | Jaleco Entertainment, NIS America | July 5, 2007 (JP) |
| Puppy Luv: Spa & Resort | Humagade | Activision | September 18, 2007 (NA) |
| Puppy Palace | Ubisoft | Ubisoft | February 5, 2008 (NA) |
| Purr Pals | Crave Entertainment | Crave Entertainment, THQ | March 27, 2007 (NA) |
| Puss in Boots | ImaginEngine | Activision | October 25, 2011 (NA) |
| Puyo Pop Fever | Sonic Team | Sega, Atlus, Ignition Entertainment | December 24, 2004 (JP) |
| Puyo Puyo 7 | Sonic Team, h.a.n.d. | Sega | July 30, 2009 (JP) |
| Puyo Puyo! 15th Anniversary | Sonic Team | Sega | December 14, 2006 (JP) |
| Puyo Puyo!! 20th Anniversary | Sonic Team | Sega | July 14, 2011 (JP) |
| Puyo Puyo Fever 2 | Sonic Team | Sega | December 24, 2005 (JP) |
| Puzzle Bobble DS | Taito Corporation | Taito Corporation | August 25, 2005 (JP) |
| Puzzle de Harvest Moon | Platinum Egg | Natsume | November 6, 2007 (NA) |
| Puzzle Kingdoms | Infinitive Interactive | Zoo Digital Publishing | May 5, 2009 (NA) |
| Puzzle Quest: Challenge of the Warlords | 1st Playable Productions | D3 Publisher | March 16, 2007 (PAL) |
| Puzzle Quest: Galactrix | Infinitive Interactive | D3 Publisher | February 24, 2009 (NA) |
| Puzzler Collection | Route 1 Games | Ubisoft, Zoo Digital Publishing | August 1, 2008 (PAL) |
| 007: Quantum of Solace | Vicarious Visions | Activision | October 31, 2008 (EU) |
| The Quest Trio | Activision | Activision | August 26, 2008 (NA) |
| Quick Yoga Training | Ubisoft | Ubisoft | August 6, 2008 (NA) |
| QuickSpot | Namco Bandai Games America | Namco, Namco Bandai Games America | February 9, 2006 (JP) |
| Quiz Magic Academy DS | Konami | Konami | September 12, 2008 (JP) |
| Quiz Magic Academy DS: Futatsu no Jikūseki | Konami | Konami | February 11, 2010 (JP) |
| Qupu!! Mame Goma! | Creative Core | Creative Core | July 16, 2009 (JP) |
| Rabbids Go Home | Ubisoft Montpellier | Ubisoft | November 1, 2009 (NA) |
| Race Driver: Create and Race | Firebrand Games | Atari, Codemasters | September 28, 2007 (PAL) |
| Race Driver: Grid | Firebrand Games | Codemasters | May 8, 2008 (NA) |
| Radiant Historia | Atlus | Atlus | November 3, 2010 (JP) |
| Rafa Nadal Tennis | Virtual Toys | Codemasters | January 5, 2007 (PAL) |
| Ragnarok Online DS | GungHo Works | GungHo Works, Xseed Games | December 18, 2008 (JP) |
| Rainbow Islands Revolution | Taito Corporation | Codemasters, Rising Star Games, Taito Corporation | December 29, 2005 (JP) |
| Ratatouille | Helixe | THQ | June 26, 2007 (NA) |
| Ratatouille: Food Frenzy | THQ | THQ | October 29, 2007 (NA) |
| Rayman DS | Ubisoft Montreal | Ubisoft | March 11, 2005 (PAL) |
| Rayman Raving Rabbids | Ubisoft Montpellier | Ubisoft | March 6, 2007 (NA) |
| Rayman Raving Rabbids 2 | Ubisoft Paris | Ubisoft | November 13, 2007 (NA) |
| Rayman Raving Rabbids TV Party | Ubisoft Paris | Ubisoft | November 18, 2008 (NA) |
| Reader Rabbit: on a Mission to Help the Lion Flowers | The Learning Company | Nordic | December 15, 2009 (NA) |
| Ready Steady Cook | Mindscape | Mindscape | August 14, 2009 (EU) |
| Real Adventures: Pet Vet | Mindscape | Mindscape | October 12, 2007 (PAL) |
| Real Adventures: Wild Horses | Koch Media | Koch Media | January 18, 2008 (PAL) |
| Real Football 2008 | Gameloft | Gameloft, Ubisoft | October 12, 2007 (PAL) |
| Real Football 2009 | Ubisoft | Ubisoft | November 4, 2008 (NA) |
| Real Time Conflict: Shogun Empires | Box Clever Interactive | Namco | November 21, 2005 (NA) |
| Really? Really! | Kadokawa Shoten | Kadokawa Shoten | June 25, 2009 (JP) |
| Red Bull BC One | Smack Down Productions | Ignition Entertainment, Playlogic Entertainment | August 28, 2008 (PAL) |
| Red Stone DS: Akaki Ishi ni Michibikareshi Monotachi | GameOn | GameOn | May 26, 2011 (JP) |
| Remindelight | Japan Art Media | Taito Corporation | September 28, 2006 (JP) |
| Resident Evil: Deadly Silence | Capcom | Capcom, Nintendo | January 19, 2006 (JP) |
| Retro Atari Classics | Taniko | Atari | March 11, 2005 (PAL) |
| Retro Game Challenge | indieszero | Bandai Namco Games, Xseed Games | November 15, 2007 (JP) |
| Rhapsody: A Musical Adventure | Nippon Ichi Software | Nippon Ichi Software, NIS America, Square Enix, Ubisoft | August 7, 2008 (JP) |
| Rhythm 'n Notes: Improve Your Music Skills | Success Corporation | Agetec, Success Corporation | January 11, 2007 (JP) |
| Rhythm de Run Run Run[1] | Alpha Unit | Alpha Unit | December 3, 2009 (JP) |
| Rhythm Heaven | Nintendo | Nintendo | July 31, 2008 (JP) |
| Ridge Racer DS | Namco | Namco | December 7, 2004 (NA) |
| Riku to Johan: Kaeta Nimai no E | fonfun | fonfun | July 3, 2008 (JP) |
| Rise of the Guardians | Torus Games | D3 Publisher | November 20, 2012 (NA) |
| River King: Mystic Valley | Marvelous Entertainment | Marvelous Entertainment, Natsume, Rising Star Games | June 28, 2007 (JP) |
| Road to Vegas | Nintendo | Midas Interactive Entertainment | August 22, 2008 (PAL) |
| Roary the Racing Car | Uacari | Avanquest | August 7, 2009 (EU) |
| Robocalypse | Vogster Entertainment | Vogster Entertainment | October 28, 2008 (NA) |
| Robots | Amaze Entertainment | Vivendi Games | February 24, 2005 (NA) |
| Rock Blast | UFO Interactive Games | UFO Interactive Games | August 5, 2008 (NA) |
| Rock Revolution | HB Studios | Konami | October 14, 2008 (NA) |
| Rockman EXE Operate Shooting Star | Capcom | Capcom | November 12, 2009 (JP) |
| Rollin' Rascals | Hoget | Majesco Entertainment, Rising Star Games | November 11, 2008 (NA) |
| Ron-Q! Highland in DS | 3 O'Clock | 3 O'Clock | August 7, 2008 (JP) |
| Rondo of Swords | Success Corporation | Atlus, Success Corporation | August 9, 2007 (JP) |
| Roogoo Attack | SpiderMonk Entertainment | SouthPeak Games | June 30, 2009 (NA) |
| Rosario + Vampire: Tanabata no Miss Yōkai Gakuen | Capcom | Capcom | March 20, 2008 (JP) |
| The Rub Rabbits! | Sonic Team | Sega | October 20, 2005 (JP) |
| Rubik's Puzzle World | Two Tribes | The Game Factory | November 11, 2008 (NA) |
| Runaway 2: The Dream of The Turtle | Cyanide | Focus Home Interactive | November 30, 2007 (PAL) |
| Rune Factory: A Fantasy Harvest Moon | Neverland Co. | Marvelous Entertainment, Natsume, Rising Star Games | August 24, 2006 (JP) |
| Rune Factory 2: A Fantasy Harvest Moon | Neverland Co. | Marvelous Entertainment, Natsume | January 3, 2008 (JP) |
| Rune Factory 3: A Fantasy Harvest Moon | Neverland Co. | Marvelous Entertainment, Natsume | October 22, 2009 (JP) |
| Russell Grant's Astrology | Sproing Media GmbH | Deep Silver | May 1, 2009 (PAL) |
| Safecracker: The Ultimate Puzzle Adventure | JoWooD Productions | DreamCatcher Games | December 3, 2009 (NA) |
| Saikin Koi shiteru? | Microvision | D3 Publisher | July 30, 2009 (JP) |
| Sailor Moon: La Luna Splende | Banpresto/OpenSesame Inc. | Bandai Namco Games | March 16, 2011 (EU) |
| Sakura Note: Ima ni Tsunagaru Mirai | Audio Games | Marvelous Entertainment | November 5, 2009 (JP) |
| Sally's Salon | Capcom | Capcom | November 4, 2008 (NA) |
| Sam Power: Firefighter | Ubisoft | Ubisoft | October 28, 2008 (NA) |
| Sam Power: Footballer | Ubisoft | Ubisoft | March 13, 2009 (EU) |
| Sam Power: Handyman | Ubisoft | Ubisoft | November 21, 2008 (EU) |
| Sam Power: Policeman | Ubisoft | Ubisoft | November 21, 2008 (EU) |
| Sands of Destruction | imageepoch | Sega | September 25, 2008 (JP) |
| Sangokushi Taisen DS | Sega | Sega | January 25, 2007 (JP) |
| Sangokushi Taisen Ten | Sega | Sega | August 7, 2008 (JP) |
| SBK: Snowboard Kids | Atlus | Atlus, Rising Star Games | November 22, 2005 (NA) |
| Schach | DTP Entertainment | DTP Entertainment | March 16, 2007 (PAL) |
| Scooby-Doo! First Frights | Torus Games | Warner Bros. Interactive Entertainment | September 22, 2009 (NA) |
| Scooby-Doo! Unmasked | THQ | THQ | October 18, 2005 (NA) |
| Scooby-Doo! Who's Watching Who? | THQ | THQ | October 16, 2006 (NA) |
| Scrabble 2007 Edition | Ubisoft | Ubisoft | September 14, 2007 (PAL) |
| Scrabble 2009 Edition | Stainless Games | Electronic Arts, Ubisoft | March 17, 2009 (NA) |
| Scribblenauts | 5th Cell | Warner Bros. Interactive | September 15, 2009 (NA) |
| Scurge: Hive | Orbital Media | SouthPeak Games | November 1, 2006 (NA) |
| SD Gundam G Generation DS | Bandai | Bandai | May 26, 2005 (JP) |
| SD Gundam G Generation: Cross Drive | Bandai Namco Games | Bandai Namco Games | August 9, 2007 (JP) |
| SD Gundam Sangokuden Brave Battle Warriors: Shin Mirisha Taisen | Bandai Namco Games | Bandai Namco Games | December 2, 2010 (JP) |
| Sea Monsters: A Prehistoric Adventure | Atomic Planet Entertainment | Destination Software | October 19, 2007 (PAL) |
| Secret Files: Tunguska | 10tacle Studios, Fusionsphere Systems | Deep Silver | May 23, 2008 (PAL) |
| Secret Files 2: Puritas Cordis | Fusionsphere Systems | Deep Silver | May 8, 2009 (EU) |
| The Secret Saturdays: Beasts of the 5th Sun | 1st Playable Productions | D3 Publisher | October 20, 2009 (NA) |
| Sega Casino | Sega | Sega | November 11, 2005 (NA) |
| Sega Superstars Tennis | Sumo Digital | Sega | March 18, 2008 (NA) |
| The Settlers | Blue Byte | Ubisoft | August 3, 2007 (NA) |
| Shakugan no Shana DS | MediaWorks | MediaWorks | March 29, 2007 (JP) |
| Shaberu! DS Oryōri Navi | Nintendo | Nintendo | July 20, 2006 (JP) |
| Shamu's Deep Sea Adventures | Activision | Activision | November 8, 2005 (NA) |
| Shaun the Sheep | Art | D3 Publisher | September 23, 2008 (NA) |
| Shaun White Snowboarding | Ubisoft Montreal | Ubisoft | November 16, 2008 (NA) |
| Sherlock Holmes: The Mystery of the Mummy | Frogwares | DreamCatcher Games, Focus Home Interactive | March 19, 2009 (PAL) |
| Shin Hisui no Shizuku: Hiiro no Kakera 2 DS | Idea Factory | Idea Factory | June 16, 2011 (JP) |
| Shin Lucky * Star Moe Drill | May 24, 2007 (JP) | ||
| Shin Megami Tensei: Devil Survivor | Atlus | Atlus | January 15, 2009 (JP) |
| Shin Megami Tensei: Devil Survivor 2 | Atlus | Atlus | July 28, 2011 (JP) |
| Shin Megami Tensei: Strange Journey | Atlus | Atlus | October 8, 2009 (JP) |
| Shining Force Feather | Flight-Plan | Sega | February 19, 2009 (JP) |
| Shining Stars: Super Starcade | Frame Studios Interactive | Destination Software, Zoo Digital Publishing | August 8, 2008 (PAL,NA) |
| Shinreigari: Ghost Hound DS | 5pb. | 5pb. | July 31, 2008 (JP) |
| Shion no Ō | NCS | NCS | April 10, 2008 (JP) |
| Shorts | Artificial Mind and Movement | Majesco Entertainment | July 11, 2009 (NA) |
| The Shouboutai | D3 Publisher | D3 Publisher | June 26, 2008 (JP) |
| Showtime Championship Boxing | Destination Software | Destination Software, Zoo Digital Publishing | November 10, 2007 (NA) |
| Shrek Forever After | Griptonite Games | Activision | May 18, 2010 (NA) |
| Shrek: Ogres & Dronkeys | WayForward Technologies | Activision | November 5, 2007 (NA) |
| Shrek Smash n' Crash Racing | Activision | Activision | March 9, 2007 (NA) |
| Shrek SuperSlam | 7 Studios, Shaba Games | Activision | October 25, 2005 (NA) |
| Shrek the Third | Vicarious Visions | Activision | May 2, 2007 (NA) |
| Shrek's Carnival Craze | Ivolgamus | Activision | October 28, 2008 (NA) |
| Shugo Chara! Amu's Rainbow-Colored Character Change! | Konami | Konami | November 6, 2008 (JP) |
| Shugo Chara! Norinori! Character Transformation zoom | Konami | Konami | August 6, 2009 (JP) |
| Signal | Studio Altair | D3 Publisher | December 3, 2009 (JP) |
| Sid Meier's Civilization Revolution | Firaxis Games | 2K Games | July 8, 2008 (NA) |
| Sigma Harmonics | Think Garage | Square Enix | August 21, 2008 (JP) |
| Silly Bandz | Zoo Games | November 23, 2010 (NA) | |
| SimAnimals | Electronic Arts | Electronic Arts | January 21, 2009 (NA) |
| SimAnimals Africa | Maxis | Electronic Arts | October 27, 2009 (NA) |
| SimCity DS | EA Japan | EA Games, Electronic Arts | February 22, 2007 (JP) |
| SimCity DS 2 | Electronic Arts | EA Games, Electronic Arts | March 19, 2008 (JP) |
| The Simpsons Game | Electronic Arts | EA Games | October 30, 2007 (NA) |
| The Sims 2 | Griptonite Games | Electronic Arts | October 24, 2005 (NA) |
| The Sims 2: Apartment Life | August 29, 2008 (NA) | ||
| The Sims 2: Apartment Pets | Electronic Arts | Electronic Arts | August 26, 2008 (NA) |
| The Sims 2: Castaway | Maxis | EA Games, Electronic Arts | October 22, 2007 (NA) |
| The Sims 2: Pets | Maxis | EA Games | October 27, 2006 (PAL) |
| The Sims 3 | The Sim Studio, Edge of Reality | Electronic Arts | October 26, 2010 (NA) |
| Six Flags Fun Park | Brash Entertainment | Brash Entertainment | October 28, 2008 (NA) |
| Skate It | Exient Entertainment | Electronic Arts | November 19, 2008 (NA) |
| Slide Adventure MAGKID | Agenda | Nintendo | August 2, 2007 (JP) |
| Slingo Quest | Mac Play | MumboJumbo | October 7, 2008 (NA) |
| Smart Boy's: Gameroom | Starfish SD | 505 Games, Starfish SD, UFO Interactive Games | April 26, 2007 (JP) |
| Smart Boy's: Toy Club | UFO Interactive Games | 505 Games, Starfish SD, UFO Interactive Games | April 24, 2008 (EU) |
| Smart Boy's: Winter Wonderland | UFO Interactive Games | UFO Interactive Games | October 28, 2008 (NA) |
| Smart Girl's: Magical Book Club | UFO Interactive Games | Tommo | November 11, 2005 (NA) |
| Smart Girl's: Party Games | UFO Interactive Games | 505 Games, Starfish SD, Tommo | October 23, 2008 (NA) |
| Smart Girl's: Playhouse | Starfish SD | 505 Games, Starfish SD, UFO Interactive Games | September 19, 2007 (NA) |
| Smart Girl's: Winter Wonderland | UFO Interactive Games | UFO Interactive Games | October 28, 2008 (NA) |
| Smart Kid's: Gameclub | UFO Interactive Games | UFO Interactive Games | November 16, 2007 (NA) |
| Smart Kid's: Party Fun Pack | Starfish SD | UFO Interactive Games | October 14, 2008 (NA) |
| The Smurfs | Ubisoft | July 19, 2011 (NA) | |
| The Smurfs 2 | Ubisoft | July 23, 2013 (NA) | |
| SNK vs. Capcom Card Fighters DS | SNK Playmore | SNK Playmore, Ignition Entertainment | December 14, 2006 (JP) |
| Snood 2: on Vacation | Rebellion | Destination Software, Zoo Digital Publishing | November 16, 2005 (NA) |
| So Blonde: Back to the Island | Wizarbox | DTP Entertainment | November 11, 2010 (PAL) |
| Solatorobo: Red the Hunter | CyberConnect2 | Bandai Namco Games, Xseed Games, Nintendo | October 28, 2010 (JP) |
| Solid Body Picross | March 12, 2009 (JP) | ||
| Solitaire Overload | Telegames | Telegames | October 26, 2007 (NA) |
| Solitaire: Ultimate Collection | Koch Media | Koch Media | April 11, 2008 (PAL) |
| Soma Bringer | Monolith Soft | Nintendo | February 28, 2008 (JP) |
| Sommelier DS | Electronic Arts | Electronic Arts | July 19, 2007 (JP) |
| Sonny with a Chance | Altron | Disney Interactive Studios | March 16, 2010 (NA) |
| Sonic & Sega All-Stars Racing | Sumo Digital | Sega | November 11, 2010 (NA) |
| Sonic Chronicles: The Dark Brotherhood | BioWare | Sega | September 26, 2008 (PAL) |
| Sonic Classic Collection | Sonic Team | Sega | March 2, 2010 (NA) |
| Sonic Colors | Dimps | Sega | November 11, 2010 (AU) |
| Sonic Rush | Dimps, Sonic Team | Sega | November 15, 2005 (NA) |
| Sonic Rush Adventure | Dimps, Sonic Team | Sega | September 14, 2007 (PAL) |
| Sora no Otoshimono Forte: Dreamy Season | Kadokawa Shoten | Kadokawa Shoten | January 27, 2011 (JP) |
| The Sorcerer's Apprentice | Headstrong Games | Disney Interactive Studios | July 13, 2010 (NA) |
| Soukoku no Kusabi: Hiiro no Kakera 3 DS | Idea Factory | Idea Factory | August 25, 2011 (JP) |
| Soul Bubbles | Mekensleep | Eidos Interactive, Interchannel | June 10, 2008 (NA) |
| Space Ace | November 11, 2008 (PAL) | ||
| Space Bust-A-Move | Lancarse, Taito Corporation | Square Enix, Taito Corporation | December 18, 2008 (JP) |
| Space Camp | 7 Studios | Activision | May 26, 2009 (NA) |
| Space Chimps | WayForward Technologies | Brash Entertainment | July 15, 2008 (NA) |
| Space Invaders Extreme | Taito Corporation | Square Enix, Taito Corporation | February 21, 2008 (JP) |
| Space Invaders Extreme 2 | Project Just | Square Enix, Taito Corporation | March 26, 2009 (JP) |
| Space Invaders Revolution | Taito Corporation | Mastiff, Taito Corporation, Rising Star Games | March 24, 2005 (JP) |
| Spanish for Everyone | Humagade | Activision | October 26, 2007 (NA) |
| Spectral Force Genesis | Idea Factory | Cyberfront, Idea Factory, Nobilis | June 19, 2008 (JP) |
| Spectrobes | Jupiter | Disney Interactive Studios | March 6, 2007 (NA) |
| Spectrobes: Beyond the Portals | Jupiter | Disney Interactive Studios | October 7, 2008 (NA) |
| Speed Racer | Virtuous Games | Activision, Warner Bros. Interactive | May 6, 2008 (NA) |
| Spellbound | 505 Games | 505 Games | September 5, 2008 (PAL) |
| Spelling Challenges and More! | Supersonic Software | Crave Entertainment | September 24, 2007 (NA) |
| Spice and Wolf: Holo's and My One Year | ASCII MediaWorks | ASCII MediaWorks | June 26, 2008 (JP) |
| Spice and Wolf: The Wind that Spans the Sea | ASCII MediaWorks | ASCII MediaWorks | September 17, 2009 (JP) |
| Spider-Man 2 | Vicarious Visions | Activision | November 21, 2004 (NA) |
| Spider-Man 3 | Vicarious Visions | Activision | May 4, 2007 (NA) |
| Spider-Man: Battle for New York | Torus Games | Activision | November 14, 2006 (NA) |
| Spider-Man: Friend or Foe | Artificial Mind and Movement | Activision | October 2, 2007 (NA) |
| Spider-Man: Web of Shadows | Griptonite Games | Activision | October 24, 2008 (NA) |
| The Spiderwick Chronicles | Stormfront Studios | Sierra Entertainment | February 5, 2008 (NA) |
| Spitfire Heroes: Tales of the Royal Air Force | Big John Games | Destineer | March 5, 2008 (NA) |
| SpongeBob SquarePants featuring Nicktoons: Globs of Doom | Natsume | THQ | October 20, 2008 (NA) |
| SpongeBob SquarePants: Creature from the Krusty Krab | WayForward Technologies | THQ | October 18, 2006 (NA) |
| SpongeBob SquarePants: The Yellow Avenger | Tantalus Media | THQ | November 7, 2005 (NA) |
| SpongeBob vs. The Big One: Beach Party Cook-Off | THQ | THQ | March 3, 2009 (NA) |
| SpongeBob's Atlantis SquarePantis | Altron | THQ | October 23, 2007 (NA) |
| SpongeBob's Boating Bash | THQ | THQ | March 2, 2010 (NA) |
| SpongeBob's Truth or Square | Heavy Iron Studios | THQ | October 26, 2009 (NA) |
| Spore Creatures | Foundation 9 | EA Games | September 4, 2008 (PAL) |
| Spore Hero Arena | Maxis | EA Games | October 6, 2009 (NA) |
| The Sports Daishuugou | D3 Publisher | D3 Publisher | December 20, 2007 (JP) |
| Sprung | Ubisoft | Ubisoft | December 8, 2004 (NA) |
| Spy Kids: All the Time in the World | OneNine Studios | Majesco | August 12, 2011 (NA) |
| Spyro: Shadow Legacy | Amaze Entertainment | Vivendi Universal Games, Sierra Entertainment | October 18, 2005 (NA) |
| Squinkies | HumanSoft | Activision | April 12, 2011 (NA) |
| Squinkies 2: Adventure Mall Surprize! | Activision | Activision | October 25, 2011 (NA) |
| Star Fox Command | Q-Games, Nintendo EAD | Nintendo | August 3, 2006 (JP) |
| Star Trek: Tactical Assault | Quicksilver Software | Bethesda Softworks | October 26, 2006 (NA) |
| Star Wars Battlefront: Elite Squadron | n-Space | LucasArts | November 3, 2009 (NA) |
| Star Wars Episode III: Revenge of the Sith | Ubisoft Montreal | Ubisoft | April 5, 2005 (NA) |
| Star Wars: Lethal Alliance | Ubisoft Montreal | Ubisoft | July 6, 2006 (NA) |
| Star Wars: The Clone Wars - Jedi Alliance | LucasArts | LucasArts | November 11, 2008 (NA) |
| Star Wars: The Clone Wars - Republic Heroes | Krome Studios, LucasArts | LucasArts | September 15, 2009 (NA) |
| Star Wars: The Force Unleashed | n-Space | Activision, LucasArts | September 16, 2008 (NA) |
| Steal Princess | Climax Entertainment | Marvelous Entertainment, Atlus, Rising Star Games | July 29, 2008 (JP) |
| Steel Horizon | Climax Group | Konami | March 20, 2007 (NA) |
| Stitch Jam | Disney Interactive Studios | Disney Interactive Studios | December 3, 2009 (JP) |
| Stratego | Ubisoft | Ubisoft | June 6, 2008 (PAL) |
| Strawberry Shortcake: Strawberryland Games | Gorilla Systems | The Game Factory | October 23, 2006 (NA) |
| Strawberry Shortcake: The Four Seasons Cake | The Game Factory | The Game Factory | November 9, 2007 (PAL) |
| Street Football | Koch Media | Koch Media | May 16, 2008 (PAL) |
| Strike Witches: Sōkū no Dengekisen - Shin Taichou Funtousuru! | Russel | Russel | November 26, 2009 (JP) |
| Strike Witches 2: Iyasu Naosu Punipunisuru | Kadokawa Shoten | Kadokawa Shoten | October 21, 2010 (JP) |
| Style Book: Cinnamoroll | Bandai | Bandai | March 23, 2006 (JP) |
| Style Book: Junior City | Bandai | Bandai | March 23, 2006 (JP) |
| Style Savvy | Syn Sophia, Nintendo SPD | Nintendo | October 23, 2008 (JP) |
| Subbuteo | Artematica | 505 Games | September 12, 2008 (PAL) |
| Sudoku Gridmaster | Hudson Soft | Hudson Soft, Nintendo | March 23, 2006 (JP) |
| Sudoku Mania | FrontLine Studios | UFO Interactive Games, Zoo Digital Publishing | June 30, 2006 (NA) |
| Sudokuro | Crave Entertainment | Crave Entertainment | May 16, 2007 (NA) |
| Suikoden Tierkreis | Konami | Konami | December 18, 2008 (JP) |
| The Suite Life of Zack & Cody: Circle of Spies | Artificial Mind and Movement | Disney Interactive Studios | October 18, 2007 (NA) |
| The Suite Life of Zack & Cody: Tipton Trouble | Artificial Mind and Movement | Buena Vista Games | September 18, 2006 (NA) |
| Suite PreCure♪: Melody Collection | Bandai | Namco Bandai Games | August 25, 2011 (JP) |
| Summon Night | Flight-Plan | Namco Bandai Games | April 24, 2008 (JP) |
| Summon Night 2 | Flight-Plan | Namco Bandai Games | August 7, 2008 (JP) |
| Summon Night X: Tears Crown | Namco Bandai Games | Namco Bandai Games | November 5, 2009 (JP) |
| Summon Night: Twin Age | Flight-Plan | Atlus, Banpresto | August 30, 2007 (JP) |
| The Sun Crossword Challenge | Mercury Games | Mercury Games | April 18, 2008 (PAL) |
| Super Black Bass: Dynamic Shot | Starfish SD | Eidos Interactive, Majesco Entertainment, Starfish SD | November 24, 2005 (JP) |
| Super Brain Tease: Football Edition | Lexicon Entertainment | Lexicon Entertainment | November 11, 2008 (PAL) |
| Super Brain Tease: Geography Edition | Lexicon Entertainment | Lexicon Entertainment | November 11, 2008 (PAL) |
| Super Brain Tease: History Edition | Lexicon Entertainment | Lexicon Entertainment | November 11, 2008 (PAL) |
| Super Brain Tease: Movies Edition | Lexicon Entertainment | Lexicon Entertainment | November 11, 2008 (PAL) |
| Super Brain Tease: Music Edition | Lexicon Entertainment | Lexicon Entertainment | November 11, 2008 (PAL) |
| Super Collapse 3 | Mac Play | MumboJumbo | October 30, 2007 (NA) |
| Super Dodgeball Brawlers | Access Co., Arc System Works | Arc System Works, Aksys Games | March 19, 2008 (JP) |
| Super Fruit Fall | Play It! | Play It!, Warner Bros. Interactive Entertainment | July 13, 2007 (PAL) |
| Super Mario 64 DS | Nintendo | Nintendo | November 20, 2004 (NA) |
| Super Monkey Ball: Touch & Roll | Sega | Sega | December 1, 2005 (JP) |
| Super Princess Peach | Tose | Nintendo | October 20, 2005 (JP) |
| Super Robot Gakuen | Banpresto | Namco Bandai Games | August 27, 2009 (JP) |
| Super Robot Taisen OG Saga: Endless Frontier | Banpresto, Monolith Soft | Namco Bandai Games, Atlus | May 29, 2008 (JP) |
| Super Robot Taisen OG Saga: Endless Frontier Exceed | Banpresto, Monolith Soft | Namco Bandai Games | February 25, 2010 (JP) |
| Super Robot Wars K | Banpresto | Namco Bandai Games | April 2, 2009 (JP) |
| Super Robot Wars L | Banpresto | Namco Bandai Games | November 25, 2010 (NA) |
| Super Robot Wars OG Saga: The Lord of Elemental | Banpresto | Namco Bandai Games | May 27, 2010 (NA) |
| Super Robot Wars W | Banpresto | Banpresto | March 1, 2007 (JP) |
| Super Scribblenauts | 5th Cell | Warner Bros. Interactive Entertainment, Konami | October 12, 2010 (NA) |
| Super Speed Machines | Midas Interactive Entertainment | Midas Interactive Entertainment | October 10, 2008 (PAL) |
| Superman Returns: The Videogame | EA Tiburon | EA Games | November 20, 2006 (NA) |
| Surf's Up | Ubisoft | Ubisoft | May 30, 2007 (NA) |
| Sushi Go Round | SouthPeak Games | Miniclip | March 26, 2010 (NA) |
| Suzuki Super-Bikes II: Riding Challenge | Kuju Entertainment | Valcon Games | July 25, 2008 (NA) |
| Suzumiya Haruhi no Chokuretsu | Sega | Sega | May 28, 2009 (JP) |
| Syberia | DreamCatcher Games | DreamCatcher Games | November 25, 2008 (NA) |
| Tabi no Yubisashi Kaiwachō DS: DS Series 1 Thai | TOSE | Nintendo | April 20, 2006 (JP) |
| Tabi no Yubisashi Kaiwachō DS: DS Series 2 Chūgoku | TOSE | Nintendo | April 20, 2006 (JP) |
| Tabi no Yubisashi Kaiwachō DS: DS Series 3 Kankoku | TOSE | Nintendo | April 20, 2006 (JP) |
| Tabi no Yubisashi Kaiwachō DS: DS Series 4 America | TOSE | Nintendo | April 27, 2006 (JP) |
| Tabi no Yubisashi Kaiwachō DS: DS Series 5 Deutsch | TOSE | Nintendo | April 27, 2006 (JP) |
| Table Game Spirits | Tasuke | Tasuke | November 10, 2005 (JP) |
| Table Game Spirits 2 | Tasuke | Tasuke | December 7, 2006 (JP) |
| Tactics Layer: Ritina Guard Senki | Ninja Studio | D3 Publisher | May 28, 2009 (JP) |
| Taiko no Tatsujin DS | Namco Bandai Games | Namco Bandai Games | July 26, 2007 (JP) |
| Tak: Mojo Mistake | THQ | THQ | October 13, 2008 (NA) |
| Tak: The Great Juju Challenge | Avalanche Software | THQ | September 19, 2005 (NA) |
| The Tale of Despereaux | Brash Entertainment | Brash Entertainment | December 2, 2008 (NA) |
| Tales of Hearts | Namco Tales Studio | Namco Bandai Games | December 11, 2008 (JP) |
| Tales of Innocence | Alfa System | Namco Bandai Games | December 6, 2007 (JP) |
| Tales of the Tempest | Dimps, Namco Tales Studio | Namco Bandai Games | October 26, 2006 (JP) |
| Tamagotchi Connection: Corner Shop | NanaOn-Sha | Atari, Bandai | September 15, 2005 (JP) |
| Tamagotchi Connection: Corner Shop 2 | NanaOn-Sha | Atari, Bandai, Namco Bandai Games America | July 27, 2006 (JP) |
| Tamagotchi Connection: Corner Shop 3 | NanaOn-Sha | Ataro, Namco Bandai Games | September 27, 2007 (JP) |
| Tangram Mania | 505 Games | 505 Games | February 14, 2008 (PAL) |
| Tank Battles | Midas Interactive Entertainment | Midas Interactive Entertainment | October 5, 2007 (PAL) |
| Tank Beat | MileStone Inc. | MileStone Inc., O3 Entertainment | November 30, 2006 (JP) |
| Tantei Kibukawa Ryosuke Jiken Tan: The Masquerade Lullaby | Genki | Genki | March 24, 2005 (JP) |
| Tao's Adventure: Curse of the Demon Seal | Konami | Konami | December 22, 2005 (JP) |
| Team Umizoomi | Black Lantern Studios | 2K Play | November 1, 2011 (NA) |
| Tecmo Bowl: Kickoff | Polygon Magic | Tecmo | November 17, 2008 (NA) |
| Teenage Mutant Ninja Turtles 3: Mutant Nightmare | Konami | Konami | November 1, 2005 (NA) |
| Teenage Zombies: Invasion of the Alien Brain Thingys! | InLight Entertainment | Ignition Entertainment | March 28, 2008 (PAL) |
| Telly Addicts | Ubisoft | Ubisoft | November 2, 2007 (PAL) |
| Tenchu: Dark Secret | Polygon Magic | From Software, Nintendo | April 6, 2006 (JP) |
| Tengai Makyō II: Manjimaru | Red Entertainment | Hudson Soft | March 9, 2006 (JP) |
| Tengen Toppa Gurren-Lagann | Konami | Konami | October 25, 2007 (JP) |
| Tennis Masters | System 3 | System 3 | February 23, 2007 (PAL) |
| Tetris DS | Nintendo | Nintendo | March 20, 2006 (NA) |
| Tetris Party Deluxe | Hudson Soft | Hudson Soft | May 25, 2010 (NA) |
| Texas Hold'em Poker | Skyworks Technologies | Majesco Entertainment | November 8, 2005 (NA) |
| Texas Hold 'Em Poker Pack | Webfoot Technologies | Summitsoft Entertainment | March 11, 2006 (NA) |
| Theme Park | Bullfrog Productions | EA Games, Electronic Arts | March 15, 2007 (JP) |
| Theresia | WorkJam | Aksys Games, Arc System Works | September 11, 2008 (JP) |
| Theta | Vitei | Nintendo | September 6, 2007 (JP) |
| Think: Train Your Brain | Eidos Interactive | Eidos Interactive | August 15, 2008 (PAL) |
| Thor: God of Thunder | WayForward Technologies | Sega | April 28, 2011 (AU) |
| Thrillville: Off the Rails | Frontier Developments | LucasArts | October 9, 2007 (NA) |
| ThunderCats | Bandai Namco Games | Bandai Namco Games | October 30, 2012 (NA) |
| Tiger Woods PGA Tour 08 | EA Sports | EA Sports | August 28, 2007 (NA) |
| Tiger Woods PGA Tour 2005 | EA Sports | EA Sports | December 14, 2004 (NA) |
| Tigerz | Magic Pockets | Ubisoft | February 26, 2008 (NA) |
| El Tigre: The Adventures of Manny Rivera | Barking Lizards Technologies | THQ | October 29, 2007 (NA) |
| Tim Stockdale's Riding Star | Eidos Interactive | Eidos Interactive | September 19, 2008 (PAL) |
| Time Ace | Trainwreck Studios | Konami | June 12, 2007 (NA) |
| Time Hollow | Tenky | Konami | March 19, 2008 (JP) |
| Tingle's Balloon Fight DS | Nintendo | Nintendo | April 11, 2007 (JP) |
| Titanic Mystery | Purple Hills | Oxygen Games | December 19, 2009 (EU) |
| Tinkerbell | Genius Sonority | Disney Interactive Studios | October 21, 2008 (NA) |
| TMNT | Ubisoft Montreal | Ubisoft | March 20, 2007 (NA) |
| Toeic Test DS Training | IE Institute | IE Institute | March 29, 2007 (JP) |
| Tokimeki Memorial Girl's Side: 1st Love | Konami | Konami | March 15, 2007 (JP) |
| Tokimeki Memorial Girl's Side: 1st Love Plus | Konami | Konami | March 12, 2009 (JP) |
| Tokimeki Memorial Girl's Side: 2nd Season | Konami | Konami | February 14, 2008 (JP) |
| Tokimeki Memorial Girl's Side: 3rd Story | Konami | Konami | June 24, 2010 (JP) |
| Tokyo Beat Down | Success | Atlus, Success | September 18, 2008 (JP) |
| Tom and Jerry Tales | Sensory Sweep Studios | Eidos Interactive, Warner Bros. Interactive Entertainment | November 7, 2006 (NA) |
| Tom Clancy's EndWar | Ubisoft Montreal | Ubisoft | November 4, 2008 (NA) |
| Tom Clancy's Splinter Cell: Chaos Theory | Ubisoft | Ubisoft | June 28, 2005 (NA) |
| Tomb Raider: Underworld | Santa Cruz Games | Eidos Interactive | November 18, 2008 (NA) |
| Tomb Raider: Legend | Crystal Dynamics | Eidos Interactive | November 10, 2006 (PAL) |
| Tomyka Hero: Rescue Force DS | Takara Tomy | Takara Tomy | November 20, 2008 (JP) |
| Tony Hawk's American Sk8land | Vicarious Visions | Activision | November 16, 2005 (NA) |
| Tony Hawk's Downhill Jam | Vicarious Visions | Activision | October 24, 2006 (NA) |
| Tony Hawk's Motion | Creat Studios | Activision | November 18, 2008 (NA) |
| Tony Hawk's Proving Ground | Vicarious Visions | Activision | October 15, 2007 (NA) |
| Toondoku | Majesco Entertainment | Eidos Interactive, Majesco Entertainment | October 26, 2007 (PAL) |
| Tootuff Mission Nadia | Atari | Atari | February 10, 2006 (PAL) |
| Top Gear: Downforce | Tantalus Media | Tantalus Media | November 11, 2008 (NA) |
| Top Gun | InterActive Vision Games | 505 Games, Mastiff, Taito Corporation | February 23, 2006 (JP) |
| Top Spin 2 | Indie Built | 2K Sports | March 29, 2006 (NA) |
| Top Spin 3 | PAM Development | 2K Sports | June 23, 2008 (NA) |
| Top Trumps Adventures: Dogs and Dinosaurs | Ironstone Partners | Ubisoft | October 12, 2007 (PAL) |
| Top Trumps: Doctor Who | Ironstone Partners | Eidos Interactive | May 16, 2008 (PAL) |
| Top Trumps Adventures: Horror and Predators | Ubisoft | Ubisoft | October 12, 2007 (PAL) |
| Tornado | SKONEC Entertainment | Ignition Entertainment | September 30, 2008 (NA) |
| Totally Spies! 2: Undercover | Atari | Atari | November 27, 2006 (NA) |
| Totally Spies! 3: Secret Agents | Atari | Atari | October 18, 2007 (NA) |
| Touch Darts | Sega | Agetec, Sega | June 15, 2007 (PAL) |
| Touch Detective | BeeWorks | 505 Game Street, Atlus, Success | April 13, 2006 (JP) |
| Touch Detective 2 ½ | BeeWorks | 505 Games, Atlus, Success | May 24, 2007 (JP) |
| Touch Dictionary | Daewon Media | Daewon Media | July 1, 2005 (KOR) |
| Touch Game Party | Taito Corporation | 505 Games, Taito Corporation | September 21, 2007 (PAL) |
| Touch Mechanic | Kando Games | Aspyr Media, Nintendo | March 24, 2009 (NA) |
| Touch Panic | May 25, 2006 (JP) | ||
| Touch the Dead | Dream On Studios | Eidos Interactive | May 16, 2007 (NA) |
| TouchMaster | Midway Games | Midway Games | June 25, 2007 (NA) |
| TouchMaster 2 | Midway Games | Midway Games | November 3, 2008 (NA) |
| TouchMaster 3 | Midway Games | Warner Bros. Interactive Entertainment | October 23, 2009 (NA) |
| TouchMaster Connect | Midway Games | Warner Bros. Interactive | December 3, 2010 (EU) |
| Touhai Densetsu - Akagi DS: Yami ni Maiorita Tensai | Culture Brain | Culture Brain | August 9, 2007 (JP) |
| Tout Savoir: CM2 | Atari | Infogrames | July 2, 2008 (PAL) |
| The Tower DS | DigiToys | DigiToys | June 26, 2008 (JP) |
| Toy Shop | Gameinvest, SeedStudios | Majesco Entertainment | April 29, 2008 (NA) |
| Toy Story 3: The Video Game | n-Space | Disney Interactive Studios | February 2, 2007 (PAL) |
| Trace Memory | Cing | Nintendo | February 24, 2005 (JP) |
| TrackMania DS | Firebrand Games | Atlus, Focus Home Interactive | November 14, 2008 (PAL,NA) |
| TrackMania Turbo: Build to Race | Firebrand Games | Atlus, Focus Home Interactive | September 24, 2010 (EU) |
| Transformers: Animated | Behaviour Interactive | Activision | October 21, 2008 (NA) |
| Transformers: Autobots | Vicarious Visions | Activision | June 19, 2007 (NA) |
| Transformers: Dark of the Moon - Autobots | Behaviour Interactive | Activision | June 14, 2011 (NA) |
| Transformers: Dark of the Moon - Decepticons | Behaviour Interactive | Activision | June 14, 2011 (NA) |
| Transformers: Deceptions | Vicarious Visions | Activision | June 19, 2007 (NA) |
| Transformers: Prime - The Game | Altron | Activision | October 30, 2012 (NA) |
| Transformers Revenge of the Fallen: Autobots | Vicarious Visions | Activision | June 23, 2009 (NA) |
| Transformers Revenge of the Fallen: Decepticons | Vicarious Visions | Activision | June 23, 2009 (NA) |
| Transformers: War for Cybertron - Autobots | Vicarious Visions | Activision | June 22, 2010 (NA) |
| Transformers: War for Cybertron - Decepticons | Vicarious Visions | Activision | June 22, 2010 (NA) |
| Trauma Center: Under the Knife | Atlus | Atlus, Nintendo | June 16, 2005 (JP) |
| Trauma Center: Under the Knife 2 | Atlus | Atlus | July 2, 2008 (JP) |
| Travel Coach: Europe 1 | HMH Hamburger Medien Haus | HMH Hamburger Medien Haus | May 22, 2008 (PAL) |
| Travel Coach: Europe 2 | HMH Hamburger Medien Haus | HMH Hamburger Medien Haus | November 11, 2008 (PAL) |
| Travel Coach: Europe 3 | HMH Hamburger Medien Haus | HMH Hamburger Medien Haus | November 11, 2008 (PAL) |
| Travel Games For Dummies | Beanbag Studios | Electronic Arts | October 28, 2008 (NA) |
| Treasure Gaust: Gaust Diver Crimson Red | Namco Bandai Games | Namco Bandai Games | July 5, 2007 (JP) |
| Treasure Gaust: Gaust Diver Deep Purple | Namco Bandai Games | Namco Bandai Games | July 5, 2007 (JP) |
| Treasure Report: Kikai Jikake no Isan | Namco Bandai Games | Namco Bandai Games | May 26, 2011 (JP) |
| Treasure World | Aspyr Media | Aspyr Media | July 2, 2009 (NA) |
| Trioncube | Namco Bandai Games | Atari, Namco Bandai Games | August 3, 2006 (JP) |
| Tropix | Capcom | Capcom | November 4, 2008 (NA) |
| True Swing Golf | Technology and Entertainment Software | Nintendo | November 10, 2005 (JP) |
| The Trump | D3 Publisher | D3 Publisher | June 22, 2006 (JP) |
| Tsubasa Chronicle | Arika | Arika | October 27, 2005 (JP) |
| Tsubasa Chronicle Vol. 2 | Arika | Arika | April 20, 2006 (JP) |
| Tsukibito | SNK Playmore | SNK Playmore | August 6, 2009 (JP) |
| Tsumiki: The Infernal Tower | Red Entertainment | Red Entertainment, Nobilis | August 30, 2007 (JP) |
| Turbo Super Stunt Squad | Monkey Bar Games | D3 Publisher | July 16, 2013 (NA) |
| Turn It Around! | 505 Games, Majesco Entertainment | 505 Game Street, Majesco Entertainment, Taito Corporation | July 20, 2006 (JP) |
| Twilight Syndrome: Kinjiratera Toshi Densetsu | Spike | Spike | July 24, 2008 (JP) |
| Uchi no 3 Shimai DS | Culture Brain | Culture Brain | April 12, 2008 (JP) |
| chi no 3 Shimai DS 2: 3 Shimai no Dekake Daisakusen | Culture Brain | Culture Brain | November 12, 2009 (JP) |
| Uchi no 3 Shimai no Karaoke Utagassen | Culture Brain | Culture Brain | September 12, 2010 (JP) |
| Ukkari o Nakusō! Bunshō Yomi Training | Intelligent Systems | Benesse | June 28, 2007 (JP) |
| Ultimate Band | Fall Line Studios | Disney Interactive Studios | November 4, 2008 (NA) |
| Ultimate Card Games | Cosmigo | Telegames | November 8, 2011 (NA) |
| Ultimate Mortal Kombat | Other Ocean Interactive | Midway Games | November 12, 2007 (NA) |
| Ultimate Puzzle Games: Sudoku Edition | Telegames | Telegames, White Park Bay | July 24, 2007 (NA) |
| Ultimate Spider-Man | Vicarious Visions | Activision, Taito Corporation | May 25, 2006 (JP) |
| Umiuru to Sudoku Shiyo! | Genterprise | Genterprise | September 25, 2008 (JP) |
| Undercover: Dual Motives | Sproing Interactive Media | DTP Entertainment, Eidos Interactive | April 25, 2008 (PAL) |
| Underground Pool | FrontLine Studios | UFO Interactive Games | January 26, 2007 (NA) |
| Underwater Attack | UFO Interactive Games | UFO Interactive Games | November 11, 2008 (NA) |
| Uno / Skip-Bo / Uno Freefall | Black Lantern Studios | Destination Software | November 16, 2006 (NA) |
| Uno 52 | Destination Software | Destination Software | October 3, 2006 (NA) |
| Unō Kaiten: Match-Bō Puzzle DS | Ertain | Ertain | June 14, 2007 (JP) |
| Unō Kids DS | November 13, 2008 (JP) | ||
| Unō no Tatsujin: Hirameki Kosodate My Angel | Namco Bandai Games | Namco Bandai Games | September 7, 2006 (JP) |
| Unō Tanren UnoTan DS: Shichida Shiki Otona no Shun Kan Training | Interchannel | Interchannel | February 22, 2007 (JP) |
| Unsolved Crimes | Now Production | Atari, Empire Interactive | September 16, 2008 (NA) |
| Up | Altron | THQ | May 26, 2009 (NA) |
| Uranai Demo Shite Miyōka DS | Hudson Soft | Hudson Soft | June 28, 2007 (JP) |
| The Urbz: Sims in the City | Griptonite Games | EA Games | November 17, 2004 (NA) |
| Urusei Yatsura: Endless Summer | Marvelous Entertainment | Marvelous Entertainment | October 20, 2005 (JP) |
| USA Today Crossword Challenge | Destineer | Destineer | May 30, 2008 (NA) |
| USA Today Puzzle Craze | Destineer | Destineer | February 10, 2009 (NA) |
| Utsukushii Nihongo no Kakikata Hanashikata DS | IE Institute | IE Institute | May 17, 2007 (JP) |
| Uwasa no Midori-kun!! Futari no Midori!? | Idea Factory | Idea Factory | August 21, 2008 (JP) |
| Uwasa no Midori-kun!! Natsu Iro Striker | Idea Factory | Idea Factory | September 20, 2007 (JP) |
| Valkyrie Profile: Covenant of the Plume | tri-Ace | Square Enix | November 1, 2008 (JP) |
| Vampire Knight DS | D3 Publisher | D3 Publisher | January 29, 2009 (JP) |
| Vegas Casino High 5! | Neko Entertainment | Bold Games, Neko Entertainment | April 27, 2007 (PAL) |
| Viewtiful Joe: Double Trouble! | Clover Studio | Capcom, Nintendo | November 2, 2005 (JP) |
| Virtual Villagers: A New Home | Last Day of Work | DTP Entertainment | April 27, 2010 (NA) |
| Vitamin X Evolution | D3 Publisher | D3 Publisher | March 27, 2008 (JP) |
| Vitamin Y | D3 Publisher | D3 Publisher | October 30, 2008 (JP) |
| Viva Piñata: Pocket Paradise | Rare | THQ | September 5, 2008 (PAL) |
| Wacky Races: Crash & Dash | Farming | Eidos Interactive, Warner Bros. Interactive Entertainment | June 17, 2008 (NA) |
| Wakabayashi Fumie no DS Kabu Lesson | Namco Bandai Games | Namco Bandai Games | June 21, 2007 (JP) |
| Wall-E | Helixe | THQ | June 24, 2008 (NA) |
| Walt Disney Pictures Presents Enchanted | Altron | Disney Interactive | November 6, 2007 (NA) |
| Wantame Uranai Channel | Capcom | Capcom | August 9, 2007 (JP) |
| Wantame Variety Channel | Capcom | Capcom | August 7, 2008 (JP) |
| Wappy Dog | Activision | Activision | November 8, 2011 (NA) |
| Warhammer 40,000: Squad Command | THQ | THQ | December 6, 2007 (AU) |
| Wario: Master of Disguise | Suzak Inc. | Nintendo | January 18, 2007 (JP) |
| WarioWare D.I.Y. |
|
Nintendo | April 29, 2009 (JP) |
| WarioWare: Touched! | Intelligent Systems | Nintendo | December 2, 2004 (JP) |
| Watashi no Happy Manner Book | Taito Corporation | Taito Corporation | April 5, 2007 (JP) |
| Watashi no Relaxuma | Rocket Company | Rocket Company | April 12, 2007 (JP) |
| The Water Horse: Legend of the Deep | Blast! Entertainment | Blast! Entertainment | April 25, 2008 (EU) |
| Wedding Dash | Zoo Games | Zoo Games | November 13, 2009 (NA) |
| Whac-A-Mole | Activision | Activision, Zoo Digital Publishing | September 21, 2005 (NA) |
| What's Cooking? with Jamie Oliver | Atari | Atari | October 21, 2008 (NA) |
| Wheel of Fortune | Griptonite Games | THQ | November 2, 2010 (NA) |
| Where in the World is Carmen Sandiego? | Strass Productions | Mindscape | August 10, 2009 (PAL) |
| Where the Wild Things Are | Amaze | Warner Bros. Interactive Entertainment | October 13, 2009 (NA) |
| Where's Waldo? The Fantastic Journey | Ludia | Ubisoft | September 22, 2009 (NA) |
| Who Wants To Be A Millionaire? 1st Edition | Ubisoft | Ubisoft | November 2, 2007 (PAL) |
| Wi-Fi Taiou Gensen Table Game DS | Hudson Soft | Hudson Soft | August 2, 2007 (JP) |
| Wi-Fi Taiou Morita Shogi DS | Hudson Soft | Hudson Soft | February 8, 2007 (JP) |
| Wi-Fi Taiou Yakuman DS | Nintendo | Nintendo | September 14, 2006 (JP) |
| Wiffle Ball | Skyworks Technologies | Destination Software | March 12, 2007 (PAL) |
| The Wild West | Happy Happening | Majesco Entertainment | August 28, 2007 (NA) |
| Windy x Windam | Success | DHM Interactive, Success | July 31, 2008 (JP) |
| Winner's Circle | Genki | Genki | October 18, 2007 (JP) |
| Winter Sports 2: The Next Challenge | 49 Games | Conspiracy Entertainment, RTL Games | November 25, 2008 (NA) |
| Winx Club Secret Diary 2009 | Konami | Konami | February 26, 2009 (EU) |
| Winx Club: Mission Echantrix | Konami | Konami | March 7, 2008 (PAL) |
| Winx Club: Saving Alfea | Little Orbit | Bandai Namco Games | October 17, 2014 (EU) |
| Winx Club: The Quest for the Codex | Konami | Konami | November 13, 2006 (NA) |
| WireWay | Konami | Konami | November 3, 2009 (NA) |
| A Witch's Tale | Hit Maker | Nippon Ichi Software | May 28, 2009 (JP) |
| The Wizard of Oz: Beyond the Yellow Brick Road | Media.Vision | D3 Publisher, Xseed Games | December 25, 2008 (JP) |
| Wizardry Asterisk: Hiiro no Fuuin | Starfish SD | Starfish SD | December 29, 2005 (JP) |
| Wizards of Waverly Place | Disney Interactive Studios | Disney Interactive Studios | August 25, 2009 (NA) |
| Wizards of Waverly Place: Spellbound | Disney Interactive Studios | Disney Interactive Studios | November 16, 2010 (NA) |
| Women's Murder Club: Games of Passion | Griptonite Games | THQ | September 22, 2009 (NA) |
| The Wonder Pets!: Save the Animals! | Black Lantern Studios | Take-Two Interactive | October 27, 2008 (NA) |
| Wonder World Amusement Park | Coyote Console | Majesco Entertainment | July 8, 2008 (NA) |
| The Woodleys Summer Sports | Eidos Interactive | Eidos Interactive | August 15, 2008 (PAL) |
| WordJong | Destineer | Destineer | November 16, 2007 (NA) |
| Wordmaster | Sarbakan Inc. | Zoo Games | August 12, 2008 (NA) |
| World Championship Poker | Crave Entertainment | 505 Games, Crave Entertainment | April 17, 2005 (NA) |
| World Cup Of Pool | Midas Interactive Entertainment | Midas Interactive Entertainment | September 26, 2008 (PAL) |
| The World Ends With You | Jupiter | Square Enix | July 27, 2007 (JP) |
| The World of Golden Eggs: Nori Nori Uta Dekichatte Kei | AQ Interactive | AQ Interactive | February 19, 2009 (JP) |
| World of Zoo | Blue Fang Games | THQ | November 5, 2009 (AU) |
| World Series of Poker 2008: Battle for the Bracelets | Left Field Productions | Activision | November 6, 2007 (NA) |
| World Snooker Championship 2007-08 | Blade Interactive | Blade Interactive | October 26, 2007 (PAL) |
| Worms: Open Warfare | Team17 | THQ | March 22, 2006 (NA) |
| Worms: Open Warfare 2 | Team17, Two Tribes B.V. | THQ | August 31, 2007 (PAL) |
| WWE SmackDown vs. Raw 2008 | Amaze Entertainment | THQ | November 9, 2007 (PAL) |
| WWE SmackDown vs. Raw 2009 | TOSE | THQ | November 7, 2008 (PAL) |
| WWE SmackDown vs. Raw 2010 | TOSE | THQ | October 20, 2009 (NA) |
| X-Men: The Official Game | Amaze Entertainment | Activision | May 16, 2006 (NA) |
| X-Men Origins: Wolverine | Griptonite Games | Activision | May 1, 2009 (NA) |
| Xenosaga I & II | Monolith Soft | Namco | March 30, 2006 (JP) |
| XG Blast! | Rising Star Games | UFO Interactive Games | November 11, 2008 (PAL) |
| Xiaolin Showdown | Razorback Developments | Konami | November 28, 2006 (NA) |
| Yakitate!! Japan | Bandai | Bandai | January 12, 2006 (JP) |
| Yakuman DS | Intelligent Systems | Nintendo | March 31, 2005 (JP) |
| Yamaha Supercross | Coyote Console | Destination Software, Zoo Digital Publishing | July 14, 2008 (NA) |
| Yamakawa Shuppansha Kanshuu: Shousetsu Nihonshi DS | Namco Bandai Games | Namco Bandai Games | June 7, 2007 (JP) |
| Yamakawa Shuppansha Kanshuu: Shousetsu Sekaishi DS | Namco Bandai Games | Namco Bandai Games | June 7, 2007 (JP) |
| Yareba de Kiru! The Micro Step - Gijutsu de Oboeru Eitango | D3 Publisher | D3 Publisher | July 26, 2007 (JP) |
| Yattaman DS 2 | Takara Tomy | Takara Tomy | October 11, 2008 (JP) |
| Yes! PreCure 5 | Bandai | Namco Bandai Games | November 29, 2007 (JP) |
| Yes! PreCure 5 GoGo! Zenin ShūGo! Dorīmu Fesutibaru | Bandai | Namco Bandai Games | October 30, 2008 (JP) |
| Yggdra Unison: Seiken Buyuuden | Sting Entertainment | Atlus | December 3, 2009 (JP) |
| Yoshi Touch & Go | Nintendo | Nintendo | January 27, 2005 (JP) |
| Yoshi's Island DS | Artoon | Nintendo | November 13, 2006 (NA) |
| Yosumin DS | Square Enix | Square Enix | November 8, 2007 (JP) |
| Ys DS | Interchannel | DHM Interactive, Interchannel | March 20, 2008 (JP) |
| Ys II DS | Interchannel | Interchannel | March 20, 2008 (JP) |
| Ys Strategy | Future Creates | Marvelous Entertainment, Rising Star Games | March 23, 2006 (JP) |
| Yu-Gi-Oh! 5D's Stardust Accelerator: World Championship 2009 | Konami | Konami | May 19, 2009 (NA) |
| Yu-Gi-Oh! 5D's World Championship 2010: Reverse of Arcadia | Konami | Konami | February 18, 2010 (JP) |
| Yu-Gi-Oh! 5D's World Championship 2011: Over the Nexus | Konami | Konami | February 24, 2011 (JP) |
| Yu-Gi-Oh! Duel Monsters: Nightmare Troubadour Yu-Gi-Oh! Nightmare TroubadourEU NA |
Konami | Konami | July 21, 2005 (JP) |
| Yu-Gi-Oh! Duel Monsters: World Championship 2007 Yu-Gi-Oh! World Championship 2007EU NA |
Konami | Atari, Konami | March 15, 2007 (JP) |
| Yu-Gi-Oh! Duel Monsters: World Championship 2008 Yu-Gi-Oh! World Championship 2008EU NA |
Konami | Konami | November 29, 2007 (JP) |
| Yu-Gi-Oh! Duel Monsters GX: Card Almanac Yu-Gi-Oh! GX: Card AlmanacEU NA |
Konami | Konami | August 9, 2007 (JP) |
| Yu-Gi-Oh! Duel Monsters GX: Spirit Summoner Yu-Gi-Oh! GX: Spirit CallerEU NA |
Konami | Konami | November 30, 2006 (JP) |
| Yukkuri Tanoshimu Otona no Jigsaw Puzzle DS: Sekai no Meiga 1: Renaissance, Baroque no Kyoshou | Interchannel | Interchannel | May 17, 2007 (JP) |
| Yukkuri Tanoshimu Otona no Jigsaw Puzzle DS: Sekai no Meiga 2: Inshou-ha, Kouki Inshou-ha no Kyoshou | Interchannel | Interchannel | May 17, 2007 (JP) |
| Yume Neko DS | Sega | Sega | April 24, 2008 (JP) |
| Yuuzai x Muzai | Bandai Namco Games | Bandai Namco Games | May 21, 2009 (JP) |
| Yu Yu Hakusho DS: Ankoku Bujutsukai Hen | Takara Tomy | Takara Tomy | September 21, 2006 (JP) |
| Zac to Ombra: Maboroshi no Yuuenchi | Konami | Konami | October 28, 2010 (JP) |
| Zaidan Houjin Nippon Kanji Nouryoku Kentei Kounin: KanKen DS | Rocket Company | Rocket Company | September 28, 2006 (JP) |
| Zendoku | Zoonami | Eidos Interactive | April 20, 2007 (EU) |
| Zenmai Zamurai | Genki | Genki | July 19, 2007 (JP) |
| Zenses Ocean | Shin'en Multimedia | The Game Factory | October 31, 2008 (PAL) |
| Zenses Rainforest | Shin'en Multimedia | The Game Factory | October 31, 2008 (PAL) |
| Zettai Karen Children DS: Dai-4 no Children | Konami | Konami | September 4, 2008 (JP) |
| Zettai Onkan Master | Hudson Soft | Hudson Soft | August 2, 2007 (JP) |
| Zettai Onkan Otoda Master | Hudson Soft | Hudson Soft | August 2, 2007 (JP) |
| Zettai Zetsumei Dangerous Jiisan DS: Dangerous Sensation | Kids Station | Kids Station | January 14, 2006 (JP) |
| Zhu Zhu Babies | Activision | Activision | November 1, 2011 (NA) |
| Zhu Zhu Pets | Activision | Activision | March 21, 2010 (NA) |
| Zhu Zhu Pets 2 | Activision | Activision | October 12, 2010 (NA) |
| Zhu Zhu Pets: Kung Zhu | Activision | Activision | October 12, 2010 (NA) |
| Zhu Zhu Pets: Quest for Zhu | Activision | Activision | September 27, 2011 (NA) |
| Zhu Zhu Princess: Carriages & Castles | Activision | Activision | February 8, 2011 (NA) |
| Zhu Zhu Puppies | Activision | Activision | March 29, 2011 (NA) |
| Zoey 101: Field Trip Fiasco | THQ | THQ | September 11, 2007 (NA) |
| Zoids Battle Colosseum | Takara Tomy | Takara Tomy | November 30, 2006 (JP) |
| Zoids Dash | Takara Tomy | Takara Tomy | June 15, 2006 (JP) |
| Zoids Saga DS: Legend of Arcadia | Tomy | Tomy | November 11, 2005 (JP) |
| The Zombie Crisis | D3 Publisher | D3 Publisher | January 31, 2008 (JP) |
| Zoobles! Spring to Life! | Now Production | Activision | November 1, 2011 (NA) |
| Zoo Hospital | Torus Games | Eidos Interactive, Majesco Entertainment | October 23, 2007 (NA) |
| Zoo Keeper | Success | Ignition Entertainment, Success | December 2, 2004 (JP) |
| Zoo Tycoon DS | THQ | Sega, THQ | October 11, 2005 (NA) |
| Zoo Tycoon 2 DS | Blue Fang Games | THQ | February 4, 2008 (NA) |
| Zoo Vet: Endangered Animals | Legacy Games | Vivendi Games | October 20, 2008 (NA) |
| Zubo | EA Bright Light | Electronic Arts | October 3, 2008 (PAL) |
| Zuma's Revenge! | PopCap Games | PopCap Games | February 21, 2012 (NA) |